Results 151 to 160 of about 9,752 (200)

Cost-effectiveness analysis of low bone mass prevention in Chinese older men with excessive alcohol consumption: a modelling study. [PDF]

BMJ Open
Lin X, Liu J, Wang L, Liu T, Zhang Y, Moriwaki K, You R.   +6 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Modern Strategies for Osteoporosis Therapy: Current Status and Prospects for Targeted Intervention. [PDF]

Int J Mol Sci
Omelchenko V, Koval V, Slazhneva N, Bondarenko N, Shatunova E, Vorobyeva M, Korolev M.   +6 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Alendronate Alters the Release of EVs by Raw 264.7 Osteoclasts. [PDF]

J Histochem Cytochem
Faria LP, Arana-Chavez VE, Holliday LS.
europepmc   +1 more source

Teleost‐specific ictacalcins exhibit similar structural organization, cation‐dependent activation, and transcriptional regulation as human S100 proteins

The FEBS Journal, EarlyView.
Calcium‐binding S100 proteins are important mediators of inflammation in humans. Distant members of this family have been recently discovered in teleost fish but their resemblance to human proteins has not been explored yet. This study demonstrates that zebrafish‐specific S100i1 and S100i2 (ictacalcins) possess identical structural organization and ...
Liz Hernández, Théo Paris, Maria Demou, Catherine Birck, Christina Begon‐Pescia, Juan Francisco Rodríguez Vidal, Sylwia D. Tyrkalska, Charlotte Bureau, Catherine Gonzalez, Juliette Gracia, Etienne Lelièvre, Victoriano Mulero, Mai Nguyen‐Chi, Laure Yatime   +13 more
wiley   +1 more source

Case Report: Osteomyelitis in a giant panda (<i>Ailuropoda melanoleuca</i>). [PDF]

Front Vet Sci
Wang C, Yang H, Wu K, Deng L, Li C, Wei R, Li C, Zhu Y, Wei M, Huang Z, Cheng Y, Chen X, Li D.   +12 more
europepmc   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

The FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal, Tomas Brom, Ivona Nečasová, Tomáš Janovič, Pavel Veverka, Naina Verma, Lukáš Uhrík, Lenka Hernychova, Ctirad Hofr   +8 more
wiley   +1 more source

From Bone Health to Lifespan: Pleiotropic Effects of Antiresorptive Agents. [PDF]

Endocrinol Metab (Seoul)
Kim KJ.
europepmc   +1 more source

Analysis of the efficacy and safety of denosumab in the treatment of patients with osteoporotic vertebral compression fractures after PVP. [PDF]

Sci Rep
Jiang Y, He B, Shang Q, Liu H, Chen W, Zhao W, Shen G, Ren H, Jiang X.   +8 more
europepmc   +1 more source