Results 151 to 160 of about 55,987 (284)

The microbiome in cancer

open access: yesiMeta, EarlyView.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin   +50 more
wiley   +1 more source

Metformin Administration Protects Against Deltoid Tendon Damage Through Activation of Notch Signaling

open access: yesiMeta, EarlyView.
Type 2 Diabetes Mellitus (T2DM) is a growing global health concern that is associated with severe complications including diabetic tendinopathy. In this study, we found that T2DM patients had a significantly higher prevalence of tendon surgery compared to non‐T2DM patients, which were alongside impaired ECM and cell adhesion. Notably, metformin‐treated
Can Liu   +16 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Smoking is a major public health concern worldwide. The toxic components of cigarettes, such as nicotine, can cause abuse, dependence, and tissue damage. This study aimed to evaluate the effects of exposure to cigarette smoke on the renal morphology of Wistar rats.
Cristiane Gomes Fernandes Freire   +9 more
wiley   +1 more source

Fast Tissue Clearing and Volume Imaging Techniques for Anatomy

open access: yesMicroscopy Research and Technique, EarlyView.
Tissue clearing and volume imaging techniques have revolutionized our ability to visualize large biological samples, but they face obstacles related to speed, tissue preservation, complexity, and the need for fluorescence labels that make them difficult to implement in anatomy and preclinical research.
Clément Ricard   +5 more
wiley   +1 more source

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