We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li +6 more
wiley +1 more source
Skeletal stem cells in bone development, homeostasis, and disease. [PDF]
Yuan G +4 more
europepmc +1 more source
Liquid‐phase transmission electron microscopy enables direct observation of nucleation and growth processes in solution. This review is dedicated to the remembrance of Helmut Cölfen and highlights recent studies on complex materials—oxides, biominerals, organic–inorganic crystals—which were central to his research activity. It summarizes key milestones,
Charles Sidhoum +5 more
wiley +1 more source
Ultrasonographic examination of the maturational effect of maternal vitamin D use on fetal clavicle bone development. [PDF]
Ozdemir F +6 more
europepmc +1 more source
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco +7 more
wiley +1 more source
Cyclophilin D, regulator of the mitochondrial permeability transition, impacts bone development and fracture repair. [PDF]
Sautchuk R +3 more
europepmc +1 more source
In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez +4 more
wiley +1 more source
Effects of 25-hydroxyvitamin D<sub>3</sub>, chondroitin sulfate and glucosamine sulfate on the growth performance, calcium and phosphorus metabolism, and bone development of weaned piglets. [PDF]
Xi Y +8 more
europepmc +1 more source
Sensorized Engineered Tissues with Built‐in Thermoregulation and Nutrient Supply
This work introduces a granular hydrogel‐based tissue engineering platform that includes a closed‐loop temperature control to maintain 37°C and sustainably releases nutrients, thereby enabling cells to retain a high viability even if stored at room temperature for up to 24 h.
Antonia Georgopoulou +5 more
wiley +1 more source
High-Intensity Physical Activity During Late Adolescence Predicts Young Adult CT-Based Finite Element Bone Strength in Emerging Adulthood: Iowa Bone Development Study. [PDF]
Kwon S +8 more
europepmc +1 more source

