Results 111 to 120 of about 4,574,239 (286)

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

FEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille, Shiva Rezaei, Julia Uffenorde, Oliver Gimm, Mohammad Ali Hosseinpour Feizi, Luiz Lehmann Coutinho, Carlos Guerrero‐Bosagna   +6 more
wiley   +1 more source

Unusual appearances of benign bone cysts : Retrospective review of 452 cases.

, 2014
This retrospective study reviewed unicameral bone cysts (UBCs) and aneurysmal cysts (ABCs) of bone with a total of 452 patients treated at Baltalimani Bone Diseases Education and Research Hospital, Turkey between 1981 and 2012.
ARIKAN, Yavuz; Baltalimani Bone Diseases Education and Research Hospital, AYCAN, Osman Emre; Baltalimani Bone Diseases Education and Research Hospital, CAMURCU, Yalkin; Baltalimani Bone Diseases Education and Research Hospital, KABUKCUOGLU, Yavuz Selim; Baltalimani Bone Diseases Education and Research Hospital, OZER, Devrim; Baltalimani Bone Diseases Education and Research Hospital   +4 more
core   +7 more sources

Surface modification of 3D‐printed polycaprolactone scaffolds with silk fibroin for bone tissue engineering

FEBS Open Bio, EarlyView.
Coating 3D‐printed PCL scaffolds with silk fibroin can improve biocompatibility and bone cell adhesion. One innovative design for tissue‐engineering scaffolds uses 3D printing technology. Here, we used polycaprolactone (PCL) filament as a biocompatible material to design a porous 3D scaffold for bone tissue engineering.
Hamed Koeini, Esmaeil Biazar, Davood Zaeifi, Reza Zeinali, Saeed Heidari‐Keshel, Amimasoud Hassanour, Helia Saheli, Arezou Mehrabi   +7 more
wiley   +1 more source

Developmental disabilities quarterly

, 2002
Spring 2001-; Description based on: Spring 2001; title from PDF caption (viewed on June 16, 2008); "Publication of the Ohio Developmental Disabilities Council bringing disability issues and accomplishments to the attention of Ohioans."; Harvested from ...
Ohio Developmental Disabilities Council.
core  

Italian Guidelines for the Diagnosis and Infectious Disease Management of Osteomyelitis and Prosthetic Joint Infections in Adults

, 2009
Bone and joint infections are recognized as difficult-to-treat infections that result in significant morbidity and mortality among patients and increased healthcare costs.
VENDITTI, Mario, S. Leone, S. Borre, F. Mazzotta, S. Esposito, M. Bassetti, E. Meani, O. F. Infectious Tropical Diseases Bone Joint Infections Committee For The Italian Society, F. Leoncini   +8 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Genetic skeletal disorders: phenotypic-genotypic characteristics and RhGH therapy responses of a pediatric cohort

Scientific Reports
This study aimed to explore the genotype-phenotype correlations in individuals with Genetic Skeletal Disorders (GSD), evaluate the efficacy of recombinant human Growth Hormone (rhGH) therapy.
Yiyun Huang, Yan Peng, Chuan Li, Bobo Xie, Xianda Wei, Baoheng Gui, Juan Meng, Shaoke Chen, Xin Fan   +8 more
doaj   +1 more source

Profilin 1 Negatively Regulates Osteoclast Migration in Postnatal Skeletal Growth, Remodeling, and Homeostasis in Mice

JBMR Plus, 2019
Profilin 1 (Pfn1), a regulator of actin polymerization, controls cell movement in a context‐dependent manner. Pfn1 supports the locomotion of most adherent cells by assisting actin‐filament elongation, as has been shown in skeletal progenitor cells in ...
Jumpei Shirakawa, Shuhei Kajikawa, Ralph T Böttcher, Mercedes Costell, Yayoi Izu, Tadayoshi Hayata, Masaki Noda, Yoichi Ezura   +7 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Analysis of femoroacetabular impingement by a triade of label-free optical spectroscopy techniques

Communications Biology
Understanding the biochemical mechanisms of hip joint diseases remains challenging. Femoroacetabular impingement (FAI) is a condition where developmental deformities of the hip joint reduce mobility and cause tissue damage, with characteristic red ...
Martin Hohmann, Lucas Kreiss, Faramarz Dehghani, Dongqin Ni, Max Gmelch, Oliver Friedrich, Lorenz Büchler, Michael Schmidt   +7 more
doaj   +1 more source