Results 111 to 120 of about 4,253,135 (331)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Ohio Early Intervention COVID-19 guidelines

, 2020
"March 12, 2020."Early intervention timelines -- Using technology -- Best practicesThe Ohio Department of Developmental Disabilities (DODD) provides the following guidelines to support Early Intervention (EI) service providers in carrying out the ...
Ohio. Department of Developmental Disabilities
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The Application of MSCs-Derived Extracellular Vesicles in Bone Disorders: Novel Cell-Free Therapeutic Strategy

Frontiers in Cell and Developmental Biology, 2020
Bone is crucial for supporting the body, protecting other organs, providing minerals, and secreting hormone to regulate other organ’s function. Bone disorders result in pain and disability, severely affecting human health, reducing the quality of life ...
Shuyu Liu, Xia Xu, Shujing Liang, Zhihao Chen, Yan Zhang, Airong Qian, Li-Fang Hu   +6 more
semanticscholar   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications [PDF]

, 2009
We describe herein some immunological properties of human fetal bone cells recently tested for bone tissue-engineering applications. Adult mesenchymal stem cells (MSCs) and osteoblasts were included in the study for comparison.
Martin, I, Arnaud Scherberich, Montjovent, MO, Scherberich, A, Scherberich, Arnaud, Lee Ann Applegate, Montjovent, Marc-Olivier, Marc-Olivier Montjovent, Scaletta, Corinne, Dominique P. Pioletti, Bocelli-Tyndall, Chiara, Martin, Ivan, Applegate, LA, Laurent-Applegate, Lee, Bocelli-Tyndall, C., Pioletti, DP, Scherberich, A., Silke Mark, Montjovent, M.O., Scaletta, C, Pioletti, Dominique P., Mark, Silke, Mark, S., Bocelli-Tyndall, C, Applegate, Lee Ann, Mark, S, Pioletti, D.P., Corinne Scaletta, Scaletta, C., Ivan Martin, Martin, I., Applegate, L.A., Chiara Bocelli-Tyndall   +32 more
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Osteopoikilia: presentation of two cases

Acta Médica del Centro, 2010
The osteopoikilosis is a rare illness characterized by an alteration of the bone remodeling. The case of two patients, members of the same family (mother and son), who suffered from this illness, is presented here.
Damaris Pérez Betancourt, Marta Pérez de Alejo Rodríguez, Dorian W. Calero Rojas   +2 more
doaj  

Mesenchymal stem cell-based tissue regeneration therapies for periodontitis

Regenerative Therapy, 2020
Periodontitis is commonly observed and is an important concern in dental health. It is characterized by a multifactorial etiology, including imbalance of oral microbiota, mechanical stress, and systemic diseases such as diabetes mellitus.
Takehito Ouchi, Taneaki Nakagawa
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Community report from the Autism and Developmental Disabilities Monitoring (ADDM) [PDF]

CDC's National Center on Birth Defects and Developmental Disabilities has been tracking ASDs for over a decade through the Autism and Developmental Disabilities Monitoring (ADDM) Network.
National Center on Birth Defects and Developmental Disabilities (Centers for Disease Control and Prevention)
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Ontogenetic perspectives on modern human long bone growth: the humerus [PDF]

, 2015
Biological anthropologists routinely infer ancient human behaviour from macroscopic skeletal markers, although the underlying relationship between bone growth and functional adaptation remains complex.
Pitfield, Rosie
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