Results 51 to 60 of about 4,574,239 (286)

A monoallelic variant in CCN2 causes an autosomal dominant spondyloepimetaphyseal dysplasia with low bone mass

Bone Research
Cellular communication network factor 2 (CCN2) is a secreted extracellular matrix-associated protein, and its aberrantly increased expression has been implicated in a diversity of diseases involving pathological processes of fibrosis, chronic ...
Shanshan Li, Rui Shao, Shufa Li, Jiao Zhao, Qi Deng, Ping Li, Zhanying Wei, Shuqin Xu, Lin Chen, Baojie Li, Weiguo Zou, Zhenlin Zhang   +11 more
doaj   +1 more source

Research progress on the role of transforming growth factor-β in tooth and craniofacial bone development and diseases

口腔疾病防治, 2022
Dental and craniofacial bone development is a highly coordinated process that is tightly controlled by genetics and influenced by complex environments.
CAI Lang, XIE Jing, ZHOU Xuedong
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Adipokines and Chronic Rheumatic Diseases: from Inflammation to Bone Involvement

, 2020
Besides its well-known role as energy storage tissue, adipose tissue is a biologically active tissue that can also be considered as an endocrine organ, as it is able to secrete adipokines.
Cantatore F. P., Corrado A., Colia R., Rotondo C., Cici D., Ripalta Colia, Daniela Cici, Addolorata Corrado, Cinzia Rotondo, Francesco Paolo Cantatore   +9 more
core   +1 more source

Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment

npj Regenerative Medicine
Osteoarthritis affects 15% of people over 65 years of age. It is characterized by articular cartilage degradation and inflammation, leading to joint pain and disability.
Hongshang Chu, Shaoyang Zhang, Zhenlin Zhang, Hua Yue, Huijuan Liu, Baojie Li, Feng Yin   +6 more
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Premenopausal risk factors for osteoporosis

, 2001
Osteoporosis is a major public health problem because of its association with fractures. Prevention of osteoporosis is of utmost importance in reducing the health and human costs related to the disease. Bone mass in adult life is determined partly by the
Walker-Bone, K., Pearson, G., Cooper, C., Karen Walker-Bone, Gill Pearson, Cyrus Cooper   +5 more
core   +1 more source

Characterization of early mouse mesenchymal stem/progenitor cells for generating cartilage and study their role in endochondral ossification [PDF]

, 2016
Mesenchymal stem/ stromal cells (MSCs) isolated from mice have allowed to address some of the major issues that could not be investigated by using human MSCs.
Jaiswal, Sumit
core   +1 more source

BMP signaling maintains auricular chondrocyte identity and prevents microtia development by inhibiting protein kinase A

eLife
Elastic cartilage constitutes a major component of the external ear, which functions to guide sound to the middle and inner ears. Defects in auricle development cause congenital microtia, which affects hearing and appearance in patients.
Ruichen Yang, Hongshang Chu, Hua Yue, Yuji Mishina, Zhenlin Zhang, Huijuan Liu, Baojie Li   +6 more
doaj   +1 more source

Research progress on the mechanism of the Hedgehog signaling pathway during mandibular development [PDF]

口腔疾病防治
The source and process of mandible development are significantly different from those of other bones in the body, and abnormal development can lead to various bone-related diseases, seriously affecting the quality of life of patients.
XU Yao, LI Wenjin
doaj   +1 more source