Results 161 to 170 of about 3,772,562 (201)
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Bone Marrow and Metabolic Bone Disease
Seminars in Musculoskeletal RadiologyAbstractThe bone marrow represents one of the largest organs in the body, with a relevant metabolic role that continues to be investigated. Numerous studies have focused on marrow adipose tissue (MAT). Evidence indicates that the bone marrow adipocytes do not only work as storage tissue but also consist of endocrine and paracrine cells, with the ...
Maria Pilar Aparisi Gómez +1 more
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Trends in Endocrinology & Metabolism, 2008
Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
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Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
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Best Practice & Research Clinical Rheumatology, 2003
Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
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Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
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MicroRNA, 2013
MicroRNAs (miRNAs), which mainly inhibit protein expression by targeting the 3'UTR (untranslated region) of mRNAs, are known to play various roles in the pathogenesis of many different types of diseases. Specifically, in bone diseases, recent emphasis has been placed on the involvement of miRNAs in the differentiation and proliferation of bone and ...
Benjamin T, Moore, Peng, Xiao
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MicroRNAs (miRNAs), which mainly inhibit protein expression by targeting the 3'UTR (untranslated region) of mRNAs, are known to play various roles in the pathogenesis of many different types of diseases. Specifically, in bone diseases, recent emphasis has been placed on the involvement of miRNAs in the differentiation and proliferation of bone and ...
Benjamin T, Moore, Peng, Xiao
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Current Neurology and Neuroscience Reports, 2004
Recent literature demonstrates an association between antiepileptic drugs (AEDs) and bone disease. Decreased bone mineral density (BMD) has been found in adults and children receiving both enzyme-inducing AEDs and valproate, which is an enzyme-inhibiting AED.
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Recent literature demonstrates an association between antiepileptic drugs (AEDs) and bone disease. Decreased bone mineral density (BMD) has been found in adults and children receiving both enzyme-inducing AEDs and valproate, which is an enzyme-inhibiting AED.
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Current Osteoporosis Reports, 2017
Bone disease is a defining characteristic of multiple myeloma (MM) and the major cause of morbidity. It manifests as lytic lesions or osteopenia and is often associated with severe pain, pathological fracture, spinal cord compression, vertebral collapse, and hypercalcemia.
Cristina, Panaroni +2 more
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Bone disease is a defining characteristic of multiple myeloma (MM) and the major cause of morbidity. It manifests as lytic lesions or osteopenia and is often associated with severe pain, pathological fracture, spinal cord compression, vertebral collapse, and hypercalcemia.
Cristina, Panaroni +2 more
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JAMA: The Journal of the American Medical Association, 1979
ABSTRACT The second volume of Metabolic Bone Disease contains seven additional essays on bone and mineral metabolism. Despite the book's title, there is in many instances a scarcity of information on bone disease. Topics previously covered in the first volume do, however, make up for this deficit to some extent.The chapter on parathyroid physiology and
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ABSTRACT The second volume of Metabolic Bone Disease contains seven additional essays on bone and mineral metabolism. Despite the book's title, there is in many instances a scarcity of information on bone disease. Topics previously covered in the first volume do, however, make up for this deficit to some extent.The chapter on parathyroid physiology and
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The British Journal of Radiology, 1954
When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
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When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
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Immunology and Allergy Clinics of North America, 2018
Systemic mastocytosis can give very different bone pictures: from osteosclerosis to osteoporosis. Osteoporosis is one of the most frequent manifestations particularly in adults and the most clinical relevant. It is often complicated by a high recurrence of mainly vertebral fragility fractures.
Orsolini, Giovanni +4 more
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Systemic mastocytosis can give very different bone pictures: from osteosclerosis to osteoporosis. Osteoporosis is one of the most frequent manifestations particularly in adults and the most clinical relevant. It is often complicated by a high recurrence of mainly vertebral fragility fractures.
Orsolini, Giovanni +4 more
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Orthopedic Clinics of North America, 1990
Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
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Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
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