Results 171 to 180 of about 792,259 (266)
Comparative Effects of Turmeric Secondary Metabolites Across Resorptive Bone Diseases. [PDF]
Wright LE +4 more
europepmc +1 more source
An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng +9 more
wiley +1 more source
RNA splicing in bone diseases: mechanisms, pathogenesis and therapeutics. [PDF]
Zheng L +5 more
europepmc +1 more source
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh +7 more
wiley +1 more source
Role of YAP/TAZ in bone diseases: A transductor from mechanics to biology. [PDF]
Chen X +5 more
europepmc +1 more source
Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim +5 more
wiley +1 more source
Computational simulations of endocrine bone diseases related to pathological glandular PTH secretion using a multi-scale bone cell population model. [PDF]
Modiz C +7 more
europepmc +1 more source
POSS‐PEG‐NHS and GSH cocrosslinked DPAV to prepare a multifunctional anticalcification valve substitute. This modification enhances mechanical properties, hemocompatibility, and re‐endothelialization while promoting anti‐inflammatory M2 macrophage infiltration and reducing calcification.
Yuqing Zhang +10 more
wiley +1 more source

