CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
Comparative analysis of autograft <i>vs</i>. synthetic bone graft in spinal fusion: a systematic review and meta-analysis. [PDF]
Alshammari AO +8 more
europepmc +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
Scaphoid Nonunion Arthroscopic-Assisted Reduction and Percutaneous Fixation With Distal Radius Autologous Bone Graft. [PDF]
Gorsky AL +5 more
europepmc +1 more source
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han +16 more
wiley +1 more source
Autologous Iliac Crest Bone Graft After Anterior Cruciate Ligament Reconstruction Failure in Patients With Both Femoral and Tibial Tunnel Enlargement. [PDF]
Wu A, He Y, Xiang S, Xiong C, Zhu W.
europepmc +1 more source
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang +13 more
wiley +1 more source
A study on the osteogenic effect of CGF membrane combined with bone graft in rabbit calvarial defects. [PDF]
Ma R +6 more
europepmc +1 more source
A Review on Bone Tumor Management: Cutting-Edge Strategies in Bone Grafting, Bone Graft Substitute, and Growth Factors for Defect Reconstruction [PDF]
Siwat Sakdejayont,1 Thanapon Chobpenthai,1 Ploy Suksirivecharuk,1 I-Fan Ninatkiattikul,1 Thanate Poosiripinyo2 1Princess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand; 2Department of Orthopaedics, Khon Kaen Hospital ...
Sakdejayont S +4 more
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