Results 181 to 190 of about 1,232,235 (303)

A hydroxyapatite-based synthetic bone graft reduces intervertebral motion at 12 months, as measured by CT-RSA, in a porcine model of ACDF. [PDF]

Brain Spine
Östman M, Försth P, Sandberg O, Höglund O, Hedenqvist P, Engqvist H, Pujari-Palmer M, Forterre F.   +7 more
europepmc   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Bone-Grafting the Mandible [PDF]

Proceedings of the Royal Society of Medicine, 1930
W, Billington, H, Round
openaire   +2 more sources

Partial C2 corpectomy with iliac/fibula bone graft and posterior instrumented fusion for C2 vertebral body lesions: An innovative approach. [PDF]

J Craniovertebr Junction Spine
Makkina C, Panicker TV, Joseph BV.
europepmc   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Hormonal Stabilization of the Bone-Metabolic Environment: Implications for Anterior Cruciate Ligament Integrity and Bone-Graft Integration. [PDF]

J Bone Metab
Koren A, Koren L.
europepmc   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Comparative assessment of the reaming characteristics of two different technologies for intramedullary bone graft harvesting. [PDF]

Arch Orthop Trauma Surg
Guttau S, Lange M, Finze R, Beimel C, Saifzadeh S, Gospos J, Wille ML, Kobbe P, Laubach M.   +8 more
europepmc   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

A bone graft substitute is effective for posterior spinal fusion in patients with juvenile or adolescent idiopathic scoliosis: a retrospective study. [PDF]

J Spine Surg
Paez CJ, Rundell AN, Steiner RP, Ritzman TF, Floccari LV.   +4 more
europepmc   +1 more source