Results 31 to 40 of about 64,929 (260)

The Role of Lingual Bone Grafting in the Treatment of Displaced Edentulous Mandibular Fracture with Severe Atrophy [PDF]

Iranian Journal of Otorhinolaryngology, 2018
Introduction: Treatment of edentulous atrophic mandible with severe atrophy is a challenge based on local conditions and systemic diseases confronted by the age group affected.
Amin Rahpeyma, Saeedeh KHajehahmadi
doaj   +1 more source

The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction

Journal of Pharmacy and Bioallied Sciences
Background: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss.
Hiroj S Bagde, Mohammad K Alam, Yazan Eid Muteb Almohammed, Sufyan Mohammed Mukhlef Almaqawid, Abdulelah Waheed Noman Alanazi, Fawaz Talal F. Alanazi, Mohammed G Sghaireen   +6 more
doaj   +1 more source

Comparative efficacy of autologous alveolar bone grafting with autologous platelet-rich plasma and without platelet-rich plasma in cleft alveolus patients

Journal of Cleft Lip Palate and Craniofacial Anomalies, 2017
Aim: The aim of this longitudinal study was to evaluate the efficacy of alveolar bone grafting with autologous platelet-rich plasma (PRP) over cancellous bone grafting alone in cleft alveolus patients.
Rohan Suhas Deshpande, Abhilasha Omprakash Yadav, Rajiv Mukund Borle, Atul Vijay Kala, S N Jajoo, Deep Thakkar   +5 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Biosilicated collagen/β-tricalcium phosphate composites as a BMP-2-delivering bone‐graft substitute for accelerated craniofacial bone regeneration

Biomaterials Research, 2021
Background Bioceramic β-tricalcium phosphate (β-TCP) is used as a bone-grafting material and a therapeutic drug carrier for treatment of bone defects in the oral and maxillofacial regions due to the osteoconductivity and biocompatibility.
Dong Keon Lee, Mi-Ran Ki, Euy Hyun Kim, Chang-Joo Park, Jae Jun Ryu, Hyon Seok Jang, Seung Pil Pack, Yun Kee Jo, Sang Ho Jun   +8 more
doaj   +1 more source

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source

A clinical study on preserving the vitality of dental pulp affected by jawbone cysts

Kouqiang hemian waike zazhi
[Objective:] To evaluate the impact of jaw cystic lesions on dental pulp tissue, providing a basis for the effective preservation of the anatomical structure and function of teeth.
WANG Xinbin, LI Yuanyuan, ZHU Hongjie, CHEN Jiu, WANG Haojun, LANG Lin   +5 more
doaj   +1 more source

Biomimetic bone grafts and substitutes: A review of recent advancements and applications

Biomedical Engineering Advances, 2023
The demand for designing an ideal bone substitute has emerged significantly to address the clinical limitations associated with the current bone grafting materials.
Sandleen Feroz, Peter Cathro, Sašo Ivanovski, Nawshad Muhammad   +3 more
doaj   +1 more source