Results 121 to 130 of about 1,033,841 (295)

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Bone grafts and implants

, 1998
Bone grafts and ...
E. ROMEO, M. CHIAPASCO
core   +2 more sources

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Cranial Nasal Bone Grafts.

, 1989
Reconstitution of the nasal scaffolding with maintenance of soft tissue proportions either following severe facial trauma or as a sequela to aesthetic rhinoplasty misadventures frequently is best achieved using the stability afforded by bone grafts ...
Hallock, Geoffrey G, MD
core   +1 more source

Comparative efficacy of non-vascularized and vascularized bone grafts, with emerging insights into bone biomaterial grafts, in scaphoid fracture nonunion treatment: A systematic review and meta-analysis

Journal of Orthopaedic Translation
Background: Scaphoid fractures are prevalent wrist injuries with significant treatment challenges, especially when get complicated by nonunion and avascular necrosis.
Reza Karimnazhand, Roshanak Shams, Ali Behmanesh, Masoud Vosough, Azadeh Gharooee Ahangar, Laura Serrano Barrenechea, Omid Mahmoudinasab, Farid Najd Mazhar   +7 more
doaj   +1 more source

Potential of autogenous or fresh-frozen allogeneic bone block grafts for bone remodelling: a histological, histometrical, and immunohistochemical analysis in rabbits

, 2017
Our aim was to compare the wound healing of autogenous bone grafts with that of fresh-frozen allogeneic block bone in rabbits. We used 25 animals. One was killed before the experiment to provide the allogeneic bone, and the remainder were killed at four ...
de Lima, V. N., O. Magro Filho, Érnica, N.M., de Lima, V.N., de Lima, VN, V.N. de Lima, Magro Filho, O, Mello-Neto, J. M., Garbin Junior, E.A., Garbin Junior, EA, E.A. Garbin Junior, Mello-Neto, JM, Magro Filho, O. [UNESP], Érnica, N. M., Momesso, G. A.C., Momesso, G. A.C. [UNESP], Mello-Neto, J. M. [UNESP], N.M. Érnica, Garbin Junior, E. A., G.A.C. Momesso, Momesso, G.A.C., J.M. Mello-Neto, Momesso, GAC, Mello-Neto, J.M., Garbin Junior, E. A. [UNESP], de Lima, V. N. [UNESP], Érnica, NM, Magro Filho, O.   +27 more
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Discussion on Bone-Grafting [PDF]

Proceedings of the Royal Society of Medicine, 1921
  +12 more sources

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Personalized bioceramic grafts for craniomaxillofacial bone regeneration

International Journal of Oral Science
The reconstruction of craniomaxillofacial bone defects remains clinically challenging. To date, autogenous grafts are considered the gold standard but present critical drawbacks.
Ana Beatriz G. de Carvalho, Maedeh Rahimnejad, Rodrigo L. M. S. Oliveira, Prabaha Sikder, Guilherme S. F. A. Saavedra, Sarit B. Bhaduri, Debby Gawlitta, Jos Malda, Darnell Kaigler, Eliandra S. Trichês, Marco C. Bottino   +10 more
doaj   +1 more source