Results 161 to 170 of about 1,033,841 (295)
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li +16 more
wiley +1 more source
Remodelling and the fate of bone grafts in shoulder instability surgery. [PDF]
Remedios S, Karpyshyn J, Wong I.
europepmc +1 more source
BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu +12 more
wiley +1 more source
Prolonged Ischemia Induces Cellular Stress, Stimulates Extracellular Matrix Remodeling and Compromises the Viability of Human Cancellous Bone Grafts. [PDF]
Menger MM +12 more
europepmc +1 more source
In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang +5 more
wiley +1 more source
Advances and applications of bone grafts in dentistry: A short review. [PDF]
Rajmalani M +5 more
europepmc +1 more source
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu +13 more
wiley +1 more source
The scientific basis of vascularized bone grafts: Models and perfusion assessments, a systematic review. [PDF]
Wölffer M +3 more
europepmc +1 more source

