Results 1 to 10 of about 2,623,950 (378)

Challenges to Improve Bone Healing Under Diabetic Conditions

open access: yesFrontiers in Endocrinology, 2022
Diabetes mellitus (DM) can affect bone metabolism and the bone microenvironment, resulting in impaired bone healing. The mechanisms include oxidative stress, inflammation, the production of advanced glycation end products (AGEs), etc.
Yiling Chen   +4 more
doaj   +2 more sources

Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds

open access: yesBioactive Materials, 2021
Bone-tissue defects affect millions of people worldwide. Despite being common treatment approaches, autologous and allogeneic bone grafting have not achieved the ideal therapeutic effect.
Guanyin Zhu   +9 more
doaj   +2 more sources

Modulation of the Inflammatory Response and Bone Healing

open access: yesFrontiers in Endocrinology, 2020
The optimal treatment for complex fractures and large bone defects is an important unsolved issue in orthopedics and related specialties. Approximately 5–10% of fractures fail to heal and develop non-unions.
Masahiro Maruyama   +7 more
doaj   +2 more sources

Modifying MSC Phenotype to Facilitate Bone Healing: Biological Approaches

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Healing of fractures and bone defects normally follows an orderly series of events including formation of a hematoma and an initial stage of inflammation, development of soft callus, formation of hard callus, and finally the stage of bone remodeling.
Stuart B. Goodman   +2 more
doaj   +2 more sources

Mechanisms and new advances in the efficacy of plant active ingredients in tendon-bone healing [PDF]

open access: yesJournal of Orthopaedic Surgery and Research
The tendon-bone interface, known as the tenosynovial union or attachment, can be easily damaged by excessive exercise or trauma. Tendon-bone healing is a significant research topic in orthopedics, encompassing various aspects of sports injuries and ...
Yuan Li, Wei Wang, Wensheng Xu
doaj   +2 more sources

The Effects of Bone Chips Dehydrated with Solvent on Healing Bone Defects [PDF]

open access: bronzeJournal of International Medical Research, 2002
The effect of bone chips dehydrated with solvent on the healing of bone defects was evaluated. Solvent-dehydrated spongiose bone chips were placed in experimentally formed cavities in the right back tibia of rabbits.
E Dayi, M Aslan, G Şimşek, AB Yilmaz
doaj   +2 more sources

Accelerated Bone Healing via Electrical Stimulation [PDF]

open access: yesAdvanced Science
Piezoelectric effect produces an electrical signal when stress is applied to the bone. When the integrity of the bone is destroyed, the biopotential within the defect site is reduced and several physiological responses are initiated to facilitate healing.
Jianfeng Sun   +4 more
doaj   +2 more sources

Bone Healing Materials in the Treatment of Recalcitrant Nonunions and Bone Defects

open access: yesInternational Journal of Molecular Sciences, 2022
The usual treatment for bone defects and recalcitrant nonunions is an autogenous bone graft. However, due to the limitations in obtaining autogenous bone grafts and the morbidity associated with their procurement, various bone healing materials have been
E. Rodríguez‐Merchán
semanticscholar   +1 more source

Macrophages—bone marrow mesenchymal stem cells crosstalk in bone healing

open access: yesFrontiers in Cell and Developmental Biology, 2023
Bone healing is associated with many orthopedic conditions, including fractures and osteonecrosis, arthritis, metabolic bone disease, tumors and periprosthetic particle-associated osteolysis.
Siyu Fan   +10 more
doaj   +1 more source

Inorganic Nanoparticles in Bone Healing Applications

open access: yesPharmaceutics, 2022
Modern biomedicine aims to develop integrated solutions that use medical, biotechnological, materials science, and engineering concepts to create functional alternatives for the specific, selective, and accurate management of medical conditions.
Alexandra-Cristina Burdușel   +4 more
semanticscholar   +1 more source

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