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MedEdPORTAL, 2013 Introduction This resource introduces students to basic concepts related to bone healing. The module is taught in the second half of the first year of our institution's undergraduate medical program.
Lindsay Davidson
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Subject-specific multivariate modeling for regenerative rehabilitation of bone healing [PDF]
APL BioengineeringRehabilitation can help promote functional restoration following surgical reconstruction of severe bone injuries, yet prescribed regimens are often conservative due to limited understanding of their impact on healing.
Kylie E. Williams +10 more
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Restoring bone healing potential [PDF]
eLifeA combination of intermittent fasting and administering Wnt3a proteins to a bone injury can rejuvenate bone repair in aged mice.
Sequeira I.
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Macrophages—bone marrow mesenchymal stem cells crosstalk in bone healing
Frontiers in Cell and Developmental Biology, 2023 Bone healing is associated with many orthopedic conditions, including fractures and osteonecrosis, arthritis, metabolic bone disease, tumors and periprosthetic particle-associated osteolysis.
Siyu Fan +10 more
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Journal of Functional Biomaterials, 2022 The tendon-to-bone interface is a special structure connecting the tendon and bone and is crucial for mechanical load transfer between dissimilar tissues.
Haihan Gao +11 more
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Frontiers in Bioengineering and Biotechnology, 2023 At present, anterior cruciate ligament (ACL) reconstruction still has a high failure rate. Tendon graft and bone tunnel surface angiogenesis and bony ingrowth are the main physiological processes of tendon-bone healing, and also the main reasons for the ...
Bin Tian, Ming Zhang, Xin Kang
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Challenges to Improve Bone Healing Under Diabetic Conditions
Frontiers in Endocrinology, 2022 Diabetes mellitus (DM) can affect bone metabolism and the bone microenvironment, resulting in impaired bone healing. The mechanisms include oxidative stress, inflammation, the production of advanced glycation end products (AGEs), etc.
Yiling Chen +4 more
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Microtomographic, histomorphometric, and molecular features show a normal alveolar bone healing process in iNOS-deficient mice along a compensatory upregulation of eNOS and nNOS isoforms [PDF]
Journal of Applied Oral Science, 2023 Inducible nitric oxide synthase (iNOS) is one of the enzymes responsible for the synthesis of nitric oxide (NO), which is an important signaling molecule with effects on blood vessels, leukocytes, and bone cells.
Carolina Fávaro FRANCISCONI +9 more
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Intramembranous bone healing process subsequent to tooth extraction in mice: micro-computed tomography, histomorphometric and molecular characterization. [PDF]
PLoS ONE, 2015 Bone tissue has a significant potential for healing, which involves a significant the interplay between bone and immune cells. While fracture healing represents a useful model to investigate endochondral bone healing, intramembranous bone healing models ...
Andreia Espindola Vieira +9 more
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Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing [PDF]
, 2020 Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing.
Brinkman, Antonia Clara Katharina +10 more
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