Results 101 to 110 of about 492,744 (310)

Three-dimensional cephalometric evaluation of maxillary growth following in utero repair of cleft lip and alveolar-like defects in the mid-gestational sheep model [PDF]

, 2006
Objective: To evaluate maxillary growth following in utero repair of surgically created cleft lip and alveolar (CLA)-like defects by means of three-dimensional (3D) computer tomographic (CT) cephalometric analysis in the mid-gestational sheep model ...
Adzick NS, Adzick NS, Bardach J, Canady JW, Canady JW, Christina Jannowitz, Dodson TB, Edgar Biemer, Engdahl E, Evans ML, Hallock GG, Hallock GG, Hans-Florian Zeilhofer, Harrison MR, Hedrick MH, Huhn EA, Julia Henke, Kaban LB, Laszlo Kovacs, Levine JP, Longaker MT, Longaker MT, Longaker MT, Longaker MT, Longaker MT, Molsted K, Moschos A. Papadopoulos, Nikolaos A. Papadopulos, Papadopoulos MA, Papadopoulos MA, Papadopulos NA, Papadopulos NA, Papadopulos NA, Papadopulos NA, Papadopulos NA, Peter Boettcher, Popesko P, Rudolf Stolla, Smith R, Stelnicki EJ, Stelnicki EJ, Stelnicki EJ, Stern M, Stern M, Sullivan WG, Waite DE   +45 more
core   +1 more source

Bone physiology and bone healing [PDF]

Neurosurgical Focus, 2002
In the not-too-distant past, spine surgeons performed spinal arthrodesis procedures and bone union would occur. This wish, however, was often not realized, and a nonunion (pseudarthrosis) developed in 10 to 45% of patients. Although the introduction of adjunctive spinal instrumentation reduced the nonunion rate, it remained significant, ranging from 5 ...
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur

International Journal of Dentistry, 2014
This study aimed at investigating if a coating of hydroxyapatite nanocrystals would enhance bone healing over time in trabecular bone. Sandblasted and acid etched titanium implants with and without a submicron thick coat of hydroxyapatite nanocrystals ...
Lory Melin Svanborg, Luiz Meirelles, Victoria Franke Stenport, Per Kjellin, Fredrik Currie, Martin Andersson, Ann Wennerberg   +6 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Different titanium surfaces modulate the bone phenotype of SaOS-2 osteoblast-like cells. [PDF]

, 2004
Commercially pure titanium implants presenting a relatively smooth, machined surface or a roughned endosseous surface show a large percentage of clinical successes.
DI DOMENICO, GILDA, DI LAURO, ALESSANDRO ESPEDITO, DI MEGLIO, FRANCA, MONTAGNANI, STEFANIA, POSTIGLIONE, LOREDANA, RAMAGLIA, LUCA   +5 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Development of a Step Counting Algorithm Using the Ambulatory Tibia Load Analysis System for Tibia Fracture Patients [PDF]

, 2018
Introduction: Ambulation can be used to monitor the healing of lower extremity fractures. However, the ambulatory behavior of tibia fracture patients remains unknown due to an inability to continuously quantify ambulation outside of the clinic.
Ackerman, Matt, Hitchcock, Robert, Kubiak, Erik, Lajevardi-Khosh, Arad, Petelenz, Tomasz, Sinclair, Sarina, Stuart, Ami, Tresco, Ben   +7 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Local Application of Strontium in a Calcium Phosphate Cement System Accelerates Healing of Soft Tissue Tendon Grafts in Anterior Cruciate Ligament Reconstruction: Experiment Using a Rabbit Model [PDF]

, 2014
Background: The healing of soft tissue tendon graft within the bone tunnel in anterior cruciate ligament (ACL) reconstruction is known to be slower than that of bone-patellar tendon-bone graft. There are attempts in accelerating the healing of the graft
Chiu, PKY, Kuang, G, Lu, WW, Yau, WP
core   +1 more source