Results 101 to 110 of about 501,666 (360)

Fracture healing following high energy tibial trauma: Ilizarov versus Taylor Spatial Frame [PDF]

, 2014
Introduction: The optimal treatment of high energy tibial fractures remains controversial and a challenging orthopaedic problem. The role of external fi xators for all these tibial fractures has been shown to be crucial. Methods: A fi ve-year consecutive
AS Rigby, CU Menakaya, E Barron, Edwards CC, Fleming B, H Sharma, Helfet DL, Inan M, Kakar S, Sarmiento A, Woll TS, Y Hadland   +11 more
core   +1 more source

Bone physiology and bone healing [PDF]

Neurosurgical Focus, 2002
In the not-too-distant past, spine surgeons performed spinal arthrodesis procedures and bone union would occur. This wish, however, was often not realized, and a nonunion (pseudarthrosis) developed in 10 to 45% of patients. Although the introduction of adjunctive spinal instrumentation reduced the nonunion rate, it remained significant, ranging from 5 ...
openaire   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur

International Journal of Dentistry, 2014
This study aimed at investigating if a coating of hydroxyapatite nanocrystals would enhance bone healing over time in trabecular bone. Sandblasted and acid etched titanium implants with and without a submicron thick coat of hydroxyapatite nanocrystals ...
Lory Melin Svanborg, Luiz Meirelles, Victoria Franke Stenport, Per Kjellin, Fredrik Currie, Martin Andersson, Ann Wennerberg   +6 more
doaj   +1 more source

Different titanium surfaces modulate the bone phenotype of SaOS-2 osteoblast-like cells. [PDF]

, 2004
Commercially pure titanium implants presenting a relatively smooth, machined surface or a roughned endosseous surface show a large percentage of clinical successes.
DI DOMENICO, GILDA, DI LAURO, ALESSANDRO ESPEDITO, DI MEGLIO, FRANCA, MONTAGNANI, STEFANIA, POSTIGLIONE, LOREDANA, RAMAGLIA, LUCA   +5 more
core  

The dental management of patients at risk of medication-related osteonecrosis of the jaw: New paradigm of primary prevention [PDF]

, 2018
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is a potentially painful and debilitating condition that can considerably affect the quality of life of patients ...
Bedogni, Alberto, Campisi, Giuseppina, Di Fede, Olga, Fusco, Vittorio, Lo Muzio, Lorenzo, Mauceri, Rodolfo, Panzarella, Vera, Sipmo Onj Board, Null   +7 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Local Application of Strontium in a Calcium Phosphate Cement System Accelerates Healing of Soft Tissue Tendon Grafts in Anterior Cruciate Ligament Reconstruction: Experiment Using a Rabbit Model [PDF]

, 2014
Background: The healing of soft tissue tendon graft within the bone tunnel in anterior cruciate ligament (ACL) reconstruction is known to be slower than that of bone-patellar tendon-bone graft. There are attempts in accelerating the healing of the graft
Chiu, PKY, Kuang, G, Lu, WW, Yau, WP
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Histologic and histomorphometric analysis of bone regeneration with bovine grafting material after 24 months of healing. A case report [PDF]

, 2018
Anorganic bovine bone mineral matrix (ABBMM) has been reported to have osteoconductive properties and no inflammatory or adverse responses when used as grafting material in sinus augmentation procedures.
Belleggia, Fabrizio, DeVillier, Patricia, Guarnieri, Renzo, Testarelli, Luca   +3 more
core   +1 more source