Results 11 to 20 of about 501,666 (360)

Amorphous calcium phosphate nanoparticles using adenosine triphosphate as an organic phosphorus source for promoting tendon–bone healing

open access: yesJournal of Nanobiotechnology, 2021
Background Rotator cuff tear (RCT) is a common problem of the musculoskeletal system. With the advantage of promoting bone formation, calcium phosphate materials have been widely used to augment tendon-bone healing.
Haoran Liao   +7 more
doaj   +1 more source

Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds

open access: yesBioactive Materials, 2021
Bone-tissue defects affect millions of people worldwide. Despite being common treatment approaches, autologous and allogeneic bone grafting have not achieved the ideal therapeutic effect.
Guanyin Zhu   +9 more
doaj   +1 more source

Strategies for promoting tendon-bone healing: Current status and prospects

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Tendon-bone insertion (TBI) injuries are common, primarily involving the rotator cuff (RC) and anterior cruciate ligament (ACL). At present, repair surgery and reconstructive surgery are the main treatments, and the main factor determining the curative ...
Chenhui Yang   +24 more
doaj   +1 more source

Complex Spatio-Temporal Interplay of Distinct Immune and Bone Cell Subsets during Bone Fracture Healing

open access: yesCells, 2023
Background: The healing of a bone injury is a highly complex process involving a multitude of different tissue and cell types, including immune cells, which play a major role in the initiation and progression of bone regeneration.
Claudia Schlundt   +7 more
doaj   +1 more source

Age-related changes to macrophages are detrimental to fracture healing in mice. [PDF]

open access: yes, 2020
The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age ...
Brazina, Sloane   +8 more
core   +2 more sources

Measuring Bone Healing: Parameters and Scores in Comparison

open access: yesBioengineering, 2023
(1) Background: Bone healing is a complex process that can not be replicated in its entirety in vitro. Research on bone healing still requires the animal model.
Nicolas Söhling   +7 more
doaj   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]

open access: yes, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Flinspach, Armin Niklas   +5 more
core   +1 more source

Biology and augmentation of tendon-bone insertion repair

open access: yesJournal of Orthopaedic Surgery and Research, 2010
Surgical reattachment of tendon and bone such as in rotator cuff repair, patellar-patella tendon repair and anterior cruciate ligament (ACL) reconstruction often fails due to the failure of regeneration of the specialized tissue ("enthesis") which ...
Lui PPY, Zhang P, Chan KM, Qin L
doaj   +1 more source

A segmental defect adaptation of the mouse closed femur fracture model for the analysis of severely impaired bone healing

open access: yesAnimal Models and Experimental Medicine, 2020
Objective To better characterize nonunion endochondral bone healing and evaluate novel therapeutic approaches for critical size defect healing in clinically challenging bone repair, a segmental defect model of bone injury was adapted from the three‐point
Amandeep Kaur   +2 more
doaj   +1 more source

Bone healing in extraction sockets covered with collagen membrane alone or associated with porcine-derived bone graft: a comparative histological and histomorphometric analysis [PDF]

open access: yes, 2017
The present paper reports data of a randomized study aimed to analyse and compare the histologic and histomorphometric aspects of bone healing in extraction sites covered with collagen membrane alone or associated with porcine-derived bone ...
De Angelis, Francesca   +6 more
core   +2 more sources

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