Results 21 to 30 of about 19,246 (265)
Research progress in the roles of Notch signaling pathway during fracture healing
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Fracture is the most common large-organ injury in humans. It takes several months or even longer from the onset to the completion of bone reconstruction. In severe cases, delayed healing or even bone discontinuity can occur.
GUO Liqiang, ZHAO Shitian, SHU Bing
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In silico Mechano-Chemical Model of Bone Healing for the Regeneration of Critical Defects: The Effect of BMP-2. [PDF]
PLoS ONE, 2015 The healing of bone defects is a challenge for both tissue engineering and modern orthopaedics. This problem has been addressed through the study of scaffold constructs combined with mechanoregulatory theories, disregarding the influence of chemical ...
Frederico O Ribeiro +4 more
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External stimulation: A potential therapeutic strategy for tendon-bone healing
Frontiers in Bioengineering and Biotechnology, 2023 Injuries at the tendon-bone interface are very common in the field of sports medicine, and healing at the tendon-bone interface is complex. Injuries to the tendon-bone interface can seriously affect a patient’s quality of life, so it is essential to ...
Shijie Fu +9 more
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Clinical Cases in Mineral and Bone Metabolism, 2016 Delayed fracture healing and nonunion occurs in up to 5-10% of all fractures, and can present a challenging clinical scenario for the treating physician. Methods for the enhancement of skeletal repair may benefit patients that are at risk of, or have experienced, delayed healing or nonunion.
Thomas A. Einhorn, Buza Ja rd
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Focus on bone healing: new strategies for improvement of bone healing [PDF]
European Journal of Trauma and Emergency Surgery, 2020 Malreduction after tibial plateau fractures mainly occurs due to insufficient visualization of the articular surface. In 85% of all C-type fractures an involvement of the posterolateral-central segment is observed, which is the main region of malreduction.
openaire +5 more sources
Bone fracture healing in mechanobiological modeling: A review of principles and methods
Bone Reports, 2017 Bone fracture is a very common body injury. The healing process is physiologically complex, involving both biological and mechanical aspects. Following a fracture, cell migration, cell/tissue differentiation, tissue synthesis, and cytokine and growth ...
Mohammad S. Ghiasi +4 more
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Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing [PDF]
European Cells & Materials, 2021 Bone healing complications such as delayed healing or non-union affect 5-10 % of patients with a long-bone fracture and lead to reduced quality of life and increased health-care costs.
A Wallimann +7 more
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A Longitudinal Low Dose μCT Analysis of Bone Healing in Mice: A Pilot Study
Advances in Orthopedics, 2014 Low dose microcomputed tomography (μCT) is a recently matured technique that enables the study of longitudinal bone healing and the testing of experimental treatments for bone repair.
Lu-Zhao Di +9 more
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Immune modulation as a therapeutic strategy in bone regeneration
Journal of Experimental Orthopaedics, 2015 We summarize research approaches and findings on bone healing and regeneration that were presented at a workshop at the 60th annual meeting of the Orthopedic Research Society (ORS) in New Orleans in 2014.
Claudia Schlundt +5 more
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Modifying MSC Phenotype to Facilitate Bone Healing: Biological Approaches
Frontiers in Bioengineering and Biotechnology, 2020 Healing of fractures and bone defects normally follows an orderly series of events including formation of a hematoma and an initial stage of inflammation, development of soft callus, formation of hard callus, and finally the stage of bone remodeling.
Stuart B. Goodman +2 more
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