Results 21 to 30 of about 216,499 (319)

Biology and augmentation of tendon-bone insertion repair

open access: yesJournal of Orthopaedic Surgery and Research, 2010
Surgical reattachment of tendon and bone such as in rotator cuff repair, patellar-patella tendon repair and anterior cruciate ligament (ACL) reconstruction often fails due to the failure of regeneration of the specialized tissue ("enthesis") which ...
Lui PPY, Zhang P, Chan KM, Qin L
doaj   +1 more source

A segmental defect adaptation of the mouse closed femur fracture model for the analysis of severely impaired bone healing

open access: yesAnimal Models and Experimental Medicine, 2020
Objective To better characterize nonunion endochondral bone healing and evaluate novel therapeutic approaches for critical size defect healing in clinically challenging bone repair, a segmental defect model of bone injury was adapted from the three‐point
Amandeep Kaur   +2 more
doaj   +1 more source

External stimulation: A potential therapeutic strategy for tendon-bone healing

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Injuries at the tendon-bone interface are very common in the field of sports medicine, and healing at the tendon-bone interface is complex. Injuries to the tendon-bone interface can seriously affect a patient’s quality of life, so it is essential to ...
Shijie Fu   +9 more
doaj   +1 more source

Research progress in the roles of Notch signaling pathway during fracture healing

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Fracture is the most common large-organ injury in humans. It takes several months or even longer from the onset to the completion of bone reconstruction. In severe cases, delayed healing or even bone discontinuity can occur.
GUO Liqiang, ZHAO Shitian, SHU Bing
doaj   +1 more source

Impaired bone healing at tooth extraction sites in CD24-deficient mice: A pilot study. [PDF]

open access: yesPLoS ONE, 2018
To use a micro-computed tomography (micro-CT) to quantify bone healing at maxillary first molar extraction sites, and test the hypothesis that bone healing is impaired in CD24-knockout mice as compared with wild-type C57BL/6J mice.Under ketamine-xylazine
Limor Avivi-Arber   +4 more
doaj   +1 more source

Histological assessment of the local effect of different concentrations of aminoguanidine hydrochloride on bone healing in rats

open access: yesDental Research Journal, 2021
Background: Nitric oxide (NO) has several functions in bone healing and affects bone metabolism. Selective inducible NO synthase (iNOS) inhibitors can be used to assess the efficacy of NO for healing of bone defects. This study sought to assess the local
Ali Reza Farhad   +4 more
doaj   +1 more source

In silico Mechano-Chemical Model of Bone Healing for the Regeneration of Critical Defects: The Effect of BMP-2. [PDF]

open access: yesPLoS ONE, 2015
The healing of bone defects is a challenge for both tissue engineering and modern orthopaedics. This problem has been addressed through the study of scaffold constructs combined with mechanoregulatory theories, disregarding the influence of chemical ...
Frederico O Ribeiro   +4 more
doaj   +1 more source

Bone fracture healing in mechanobiological modeling: A review of principles and methods

open access: yesBone Reports, 2017
Bone fracture is a very common body injury. The healing process is physiologically complex, involving both biological and mechanical aspects. Following a fracture, cell migration, cell/tissue differentiation, tissue synthesis, and cytokine and growth ...
Mohammad S. Ghiasi   +4 more
doaj   +1 more source

Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing [PDF]

open access: yesEuropean Cells & Materials, 2021
Bone healing complications such as delayed healing or non-union affect 5-10 % of patients with a long-bone fracture and lead to reduced quality of life and increased health-care costs.
A Wallimann   +7 more
doaj   +1 more source

Bone healing in 2016

open access: yesClinical Cases in Mineral and Bone Metabolism, 2016
Delayed fracture healing and nonunion occurs in up to 5-10% of all fractures, and can present a challenging clinical scenario for the treating physician. Methods for the enhancement of skeletal repair may benefit patients that are at risk of, or have experienced, delayed healing or nonunion.
Thomas A. Einhorn, Buza Ja rd
openaire   +2 more sources

Home - About - Disclaimer - Privacy