Results 71 to 80 of about 2,623,950 (378)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

The Future of Bone Healing

Clinics in Podiatric Medicine and Surgery, 2005
With more than 5.5 million fractures and 1 million bone repair surgeries annually, bone graft plays a significant role in aiding fracture repair. In the United States alone, surgeons perform an estimated 500,000 to 600,000 bone grafting procedures annually.
openaire   +3 more sources

Bone healing after median sternotomy: A comparison of two hemostatic devices

Journal of Cardiothoracic Surgery, 2010
Background Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
Vind-Kezunovic Stefan, Jensen Henrik, Vestergaard Rikke F, Jakobsen Thomas, Søballe Kjeld, Hasenkam John M   +5 more
doaj   +1 more source

Methods for evaluation of early bone healing at titanium implants [PDF]

, 2007
Titanium has for a long time been the implant material of choice when in need for abilities as strength, biocompatibility and stability. Although numbers of studies have been made, little is known about the early events in implant healing.
Hederstierna, Karin
core   +1 more source

Developmentally Engineered Callus Organoid Bioassemblies Exhibit Predictive In Vivo Long Bone Healing

Advancement of science, 2019
Clinical translation of cell‐based products is hampered by their limited predictive in vivo performance. To overcome this hurdle, engineering strategies advocate to fabricate tissue products through processes that mimic development and regeneration, a ...
Gabriella Nilsson Hall, L. Mendes, Charikleia Gklava, L. Geris, F. Luyten, I. Papantoniou   +5 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

An appropriate Wnt/β-catenin expression level during the remodeling phase is required for improved bone fracture healing in mice

Scientific Reports, 2017
Accumulating evidence demonstrates that the Wnt/β-catenin signaling pathway plays a dominant role in bone repair. However, the role of Wnt/β-catenin signaling in the remodeling phase during bone fracture healing is currently unknown. In the present study,
Quanwei Bao, Sixu Chen, Hao Qin, Jianquan Feng, Huayu Liu, Daocheng Liu, Ang Li, Yue Shen, Yufeng Zhao, Junfeng Li, Zhaowen Zong   +10 more
doaj   +1 more source

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice. [PDF]

PLoS ONE, 2016
Following bone fracture, the repair process starts with an inflammatory reaction at the fracture site. Fracture healing is disturbed when the initial inflammation is increased or prolonged, whereby, a balanced inflammatory response is anticipated to be ...
Anna E Rapp, Ronny Bindl, Stefan Recknagel, Annika Erbacher, Ingo Müller, Hubert Schrezenmeier, Christian Ehrnthaller, Florian Gebhard, Anita Ignatius   +8 more
doaj   +1 more source

The role of peptides in bone healing and regeneration: A systematic review [PDF]

, 2016
Background: Bone tissue engineering and the research surrounding peptides has expanded significantly over the last few decades. Several peptides have been shown to support and stimulate the bone healing response and have been proposed as therapeutic ...
A Au, A Bitschnau, A Horii, A Kasaj, A Kubler, A Memeo, A Mesfin, A Mota, A Oteo-Alvaro, A Rezania, A Rezania, A Saito, A Scarano, A Shekaran, A Spreafico, A Verheyen, A Vignery, AA Sawyer, AC Karaplis, AM Wojtowicz, Anastasios Lampropoulos, AR El-Ghannam, AU Dignass, B Elmengaard, B Elmengaard, B Mognetti, B Olszewska-Pazdrak, BH Vickery, BK Culpepper, BK Culpepper, BM Hanratty, BP Sherman, C Trasatti, CC Wu, CD Reyes, CD Reyes, CG Trejo, CT Yu, D Moher, D Paridis, DJ Hak, DM Ferris, E Garreta, E Jimi, E Mrak, E Peggion, E Ruoslahti, E Smith, EA Cavalcanti-Adam, ED Karagiannis, EF Morgan, EL Hedberg, Elena Jones, EM Lindley, EP Barboza, F Butz, F Fukuda, F Gelain, F Gomar, FA Suaid, G An, G Balasundaram, G Balasundaram, G Cakmak, G Li, G Li, G Tian, G Xu, G Zimmermann, Giorgio Maria Calori, GM Calori, GN Onuoha, H Ceylan, H Drissi, H Drissi, H Egusa, H Emam, H Huang, H Misawa, H Nakahara, H Nguyen, H Shin, H Tachiiri, H Wang, HH Rowshan, I Bab, I Bab, I El-Madany, I Millet, I Pountos, I Pountos, I Pountos, I Pountos, I Pountos, I Villa, IJ Ezquerro, Ippokratis Pountos, J Guan, J Guo, J Holm, J Jo, J Jo, J Li, J Strnad, JA Guimaraes, JA Lee, JC Chang, JD Bashutski, JD Smucker, JE Madsen, JF Whitfield, JM Anderson, JM Latzman, JS Suh, JT Ryaby, JW Calland, JW Park, JY Lee, JY Lee, JY Lee, JY Lee, JY Lee, K Nozaka, K Ochi, K Sarahrudi, K Tamai, KC Dee, KC Dee, KD Hankenson, KL Ong, KM Hennessy, KM Hennessy, KM Park, L Kruger, L Pietrogrande, L Wang, L Zhang, LB Priddy, LF Castro de, LR Amir, M Amling, M Degidi, M Deng, M Gelbart, M Gilbert, M Giorgio Calori, M Ikeno, M Kantlehner, M Komrakova, M Nelson, M Ozeki, M Panteli, M Roberto-Rodrigues, M Ronga, M Schuler, M Shuqiang, M Thorwarth, M Thorwarth, MA Brager, MB Murphy, MC Durrieu, MC Simmonds, ME Cupp, Michalis Panteli, MK Shin, ML Bhongade, MM Martino, MP Bostrom, MP Bostrom, MR Sheller, N Fukushima, N Gabarin, N Mardas, N Tomomatsu, O Ashman, P Aspenberg, P Aspenberg, P Du, P Philippart, Peter V. Giannoudis, PT Rubery, PV Giannoudis, Q Fei, Q Liu, Q Zhao, R Ballica, R Visser, R Yoshimi, R Yukna, R Zura, RA Stile, RA Yukna, RA Yukna, RA Yukna, RE Dent-Acosta, RE Jung, RN Palchesko, RR Barros, RS Bhatnagar, S Cakarer, S Chintamaneni, S Dai, S Hofmann, S Komatsubara, S Matos, S Rammelt, S Schutzenberger, S Sun, S Vastardis, S Zhang, S Zheng, SG Amara, SH Park, SJ Gomberg, SJ Sample, SP Massia, SY Yoo, T Fujita, T Goff, T Hanks, T Hayashibara, T Hou, T Manabe, T Schinke, T Vordemvenne, TD Sargeant, TJ Martin, W Li, W Schneiders, W Thein-Han, X Li, XB Yang, Y Furuya, Y Gabet, Y Hamada, Y Hamada, Y Song, Y Wang, YH Wang, YJ Kim, YJ Kim, YM Alkhiary, YQ Sun, Z Artzi, Z Artzi, Z Chen, Z Dahabreh, Z Greenberg, Z Li, ZX Chen, ZY Zhao   +250 more
core   +2 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source