Results 1 to 10 of about 906,794 (309)

Bone Health for Gynaecologists. [PDF]

open access: yesMedicina (Kaunas)
Osteoporosis, the most common bone disorder, profoundly impacts women’s health, especially during postmenopausal phases. Characterised by diminished bone mineral density (BMD), it increases the risk of fractures, affecting mobility, quality of life, and potentially mortality.
Yordanov A   +4 more
europepmc   +4 more sources

Preliminary Results of Universiti Sultan Zainal Abidin Community Bone Health Screening in Manir, Kuala Terengganu using Bone Densitometry Calcaneal Quantitative Ultrasound (QUS) in Conjunction with Clinical Risk Factors [PDF]

open access: yesMalaysian Orthopaedic Journal, 2023
I am writing to bring attention to the issue of fragility fractures in the growing aged population of Malaysia. According to the International Osteoporosis Foundation, up to 70% of people are at risk and underdiagnosed with osteoporosis.
Kamudin NAF   +2 more
doaj   +1 more source

Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity

open access: yesCell Death and Disease, 2022
Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by degeneration of the tissue.
Roman J. Krawetz   +9 more
doaj   +1 more source

Consensus for a primary care clinical decision-making tool for assessing, diagnosing, and managing shoulder pain in Alberta, Canada

open access: yesBMC Family Practice, 2021
Background Shoulder pain is a highly prevalent condition and a significant cause of morbidity and functional disability. Current data suggests that many patients presenting with shoulder pain at the primary care level are not receiving high quality care.
Breda H. F. Eubank   +5 more
doaj   +1 more source

Exogenously delivered iPSCs disrupt the natural repair response of endogenous MPCs after bone injury

open access: yesScientific Reports, 2023
Promoting bone healing including fracture non-unions are promising targets for bone tissue engineering due to the limited success of current clinical treatment methods.
Leah Ferrie   +8 more
doaj   +1 more source

Characterization of miR-335-5p and miR-335-3p in human osteoarthritic tissues

open access: yesArthritis Research & Therapy, 2023
Objective We aimed to characterize the expression patterns, gene targets, and functional effects of miR-335-5p and miR-335-3p among seven primary human knee and hip osteoarthritic tissue types.
Thomas G. Wilson   +5 more
doaj   +1 more source

Mesenchymal progenitor cells from non-inflamed versus inflamed synovium post-ACL injury present with distinct phenotypes and cartilage regeneration capacity

open access: yesStem Cell Research & Therapy, 2023
Background Osteoarthritis (OA) is a chronic debilitating disease impacting a significant percentage of the global population. While there are numerous surgical and non-invasive interventions that can postpone joint replacement, there are no current ...
Roman J. Krawetz   +8 more
doaj   +1 more source

Proteoglycan 4 (PRG4) treatment enhances wound closure and tissue regeneration

open access: yesnpj Regenerative Medicine, 2022
The wound healing response is one of most primitive and conserved physiological responses in the animal kingdom, as restoring tissue integrity/homeostasis can be the difference between life and death.
Roman J. Krawetz   +15 more
doaj   +1 more source

Adolescent Bone Health [PDF]

open access: yesArchives of Pediatrics & Adolescent Medicine, 2006
Pediatric and adolescent care professionals have increasingly recognized the importance of understanding the skeletal health of their patients. Peak bone mass, the "bone bank" on which an individual will draw for their entire adult life, is likely achieved by late adolescence, with the critical window for accumulation occurring much earlier.
Keith J, Loud, Catherine M, Gordon
openaire   +2 more sources

Synovial fluid mesenchymal progenitor cells from patients with juvenile idiopathic arthritis demonstrate limited self-renewal and chondrogenesis

open access: yesScientific Reports, 2022
Juvenile idiopathic arthritis (JIA) is a heterogeneous group of inflammatory diseases affecting joints with a prevalence of one in a thousand children.
Roman J. Krawetz   +6 more
doaj   +1 more source

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