Results 21 to 30 of about 171,536 (162)

Ontogenetic stages of ceratopsian dinosaur Psittacosaurus in bone histology [PDF]

open access: yesActa Palaeontologica Polonica, 2019
The early ceratopsians Psittacosaurus and Protoceratops have provided important information on dinosaurian development because of abundant specimens of adults, subadults, juveniles, and even hatchlings.
Qi Zhao   +3 more
doaj   +1 more source

Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway

open access: yesJournal of Orthopaedic Translation, 2023
Background: It has been demonstrated that vitamin D deficiency is associated with an increased risk of patients developing lumbar disc herniation. However, intervertebral disc degeneration caused by active vitamin D deficiency has not been reported. Thus,
Peng Wang   +5 more
doaj   +1 more source

Spatial Organization of Osteoclastic Coupling Factors and Their Receptors at Human Bone Remodeling Sites

open access: yesFrontiers in Molecular Biosciences, 2022
The strictly regulated bone remodeling process ensures that osteoblastic bone formation is coupled to osteoclastic bone resorption. This coupling is regulated by a panel of coupling factors, including clastokines promoting the recruitment, expansion, and
Xenia G. Borggaard   +10 more
doaj   +1 more source

Histologic diagnosis of metabolic bone diseases: bone histomorphometry

open access: yesReumatismo, 2011
Histomorphometry or quantitative histology is the analysis on histologic sections of bone resorption parameters, formation and structure. It is the only technique that allows a dynamic evaluation of the activity of bone modelling after labelling with tetracycline.
DALLE CARBONARE, Luca Giuseppe   +1 more
openaire   +5 more sources

Effect of extracellular matrix and dental pulp stem cells on bone regeneration with 3D printed PLA/HA composite scaffolds [PDF]

open access: yesEuropean Cells & Materials, 2021
The demand for bone grafting procedures in various fields of medicine is increasing. Existing substitutes in clinical practice do not meet all the criteria required for an ideal bone scaffold, so new materials are being sought. This study evaluated bone
I Gendviliene   +8 more
doaj   +1 more source

Active Vitamin D Insufficiency Accelerates Skeletal Aging via Oxidative Stress and p16-Mediated Senescence

open access: yesFrontiers in Bioscience-Landmark
Background: Vitamin D is essential for skeletal health, but its role in redox homeostasis and cellular senescence during aging in vivo is unclear.
Wanxin Qiao   +4 more
doaj   +1 more source

The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis

open access: yesJournal of Orthopaedic Translation
Background: Objective: Vitamin D insufficiency is a major contributor to osteoporosis. This study aimed to elucidate the mechanisms by which the vitamin D-Sirt1/PGC1α axis regulates bone metabolism and counteracts osteoporosis induced by active vitamin D
Cuicui Yang   +4 more
doaj   +1 more source

Analysis of histology-agnostic targets among soft tissue and bone sarcomas in the AACR GENIE database

open access: yesFrontiers in Oncology, 2023
BackgroundThe development of novel therapies for patients with sarcoma is challenging due to the rarity and diversity of these mesenchymal neoplasms. Hence, histology-agnostic approvals can be of particular interest for the treatment of patients with ...
Roberto Carmagnani Pestana   +2 more
doaj   +1 more source

Evaluation of a New Porcine Bone Graft on the Repair of Surgically Created Critical Bone Defects in Rat Calvaria: Histomorphometric and Microtomographic Study

open access: yesJournal of Functional Biomaterials, 2022
The aim of this study was to evaluate the use of a new porcine bone graft in rat calvaria bone defects. Critical defects were surgically created in 24 rats that were divided into four experimental groups according to defect filling (n = 6): Control Group
Ytalo Fernandes   +7 more
doaj   +1 more source

Comprehensive histological evaluation of bone implants [PDF]

open access: yesBiomatter, 2014
To investigate and assess bone regeneration in sheep in combination with new implant materials classical histological staining methods as well as immunohistochemistry may provide additional information to standard radiographs or computer tomography. Available published data of bone defect regenerations in sheep often present none or sparely labeled ...
Rentsch, Claudia   +4 more
openaire   +3 more sources

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