Results 31 to 40 of about 283,173 (311)

First record of palaeopathologies in appendicular bones of the Triassic pseudosuchians Erpetosuchidae and Aetosauria based on microstructural approaches [PDF]

Acta Palaeontologica Polonica
Pseudosuchians were the dominant group of archosaurs on continental ecosystems during the Triassic. However, studies that report palaeopathologies based on osteohistological evidence in this group are scarce. Here, two cases of palaeopathologies found in
Denis A. Ponce, Ignacio A. Cerda, Julia B. Desojo   +2 more
doaj   +1 more source

Effect of extracellular matrix and dental pulp stem cells on bone regeneration with 3D printed PLA/HA composite scaffolds [PDF]

European Cells & Materials, 2021
The demand for bone grafting procedures in various fields of medicine is increasing. Existing substitutes in clinical practice do not meet all the criteria required for an ideal bone scaffold, so new materials are being sought. This study evaluated bone
I Gendviliene, E Simoliunas, M Alksne, S Dibart, E Jasiuniene, V Cicenas, R Jacobs, V Bukelskiene, V Rutkunas   +8 more
doaj   +1 more source

Bone substitute effect on vascularization and bone remodeling after application of phVEGF165 transfected BMSC [PDF]

, 2012
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming capacities of VEGF transfected bone marrow ...
Beverungen, Mirjam, Fehr, Michael, Geiger, Florian, Kasten, Philip, Lorenz, Helga, Wieland, Julia   +5 more
core   +2 more sources

Intra- and Extra-articular Features of Temporomandibular Joint Ankylosis in the Cat (Felis catus). [PDF]

, 2020
Temporomandibular joint (TMJ) ankylosis is an uncommon clinical entity in human and veterinary medicine. However, the condition is severely debilitating and is life-limiting if not treated. This study sought to characterize the intra- and extra-articular
Arzi, B, Garcia, T, Hatcher, DC, Vapniarsky, N, Verstraete, FJM, Zavodovskaya, R   +5 more
core  

Active Vitamin D Insufficiency Accelerates Skeletal Aging via Oxidative Stress and p16-Mediated Senescence

Frontiers in Bioscience-Landmark
Background: Vitamin D is essential for skeletal health, but its role in redox homeostasis and cellular senescence during aging in vivo is unclear.
Wanxin Qiao, Mingxin Huang, Lulu Chen, David Goltzman, Dengshun Miao   +4 more
doaj   +1 more source

The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis

Journal of Orthopaedic Translation
Background: Objective: Vitamin D insufficiency is a major contributor to osteoporosis. This study aimed to elucidate the mechanisms by which the vitamin D-Sirt1/PGC1α axis regulates bone metabolism and counteracts osteoporosis induced by active vitamin D
Cuicui Yang, Lulu Chen, Xiaoli Guo, Haijian Sun, Dengshun Miao   +4 more
doaj   +1 more source

Efficacy of temsirolimus in metastatic chromophobe renal cell carcinoma [PDF]

, 2013
<p>Background: Renal cell carcinoma (RCC) is a histopathologically and molecularly heterogeneous disease with the chromophobe subtype (chRCC) accounting for approximately 5% of all cases.
A Armstrong, A Jemal, B Paule, B Shuch, Balaji Venugopal, D Zardavas, G Hudes, G Kovacs, J Dutcher, J-J Patard, Jawaher Ansari, JMG Larkin, Lye Mun Tho, ME Gore, Michael Aitchison, PH Patel, RJ Motzer, RJ Motzer, Rob J Jones, Roderick Campbell, SK Tickoo, TK Choueiri   +21 more
core   +1 more source

Analysis of histology-agnostic targets among soft tissue and bone sarcomas in the AACR GENIE database

Frontiers in Oncology, 2023
BackgroundThe development of novel therapies for patients with sarcoma is challenging due to the rarity and diversity of these mesenchymal neoplasms. Hence, histology-agnostic approvals can be of particular interest for the treatment of patients with ...
Roberto Carmagnani Pestana, César Serrano, César Serrano   +2 more
doaj   +1 more source

In Vivo Corrosion of Two Novel Magnesium Alloys ZEK100 and AX30 and Their Mechanical Suitability as Biodegradable Implants [PDF]

, 2011
In magnesium alloys, the components used modify the alloy properties. For magnesium implants in contact with bone, rare earths alloys are commonly examined.
Angrisani, Nina, Bormann, Dirk, Huehnerschulte, Tim Andreas, Meyer-Lindenberg, Andrea, Rittershaus, Dina, Windhagen, Henning   +5 more
core   +3 more sources

Preliminary bone histological analysis of Lystrosaurus (Therapsida: Dicynodontia) from the Lower Triassic of North China, and its implication for lifestyle and environments after the end-Permian extinction.

PLoS ONE, 2021
Lystrosaurus represents one of the most successful dicynodonts, a survivor of the end-Permian mass extinction that remained abundant in the Early Triassic, but many aspects of its paleobiology are still controversial.
Fenglu Han, Qi Zhao, Jun Liu
doaj   +1 more source