Results 41 to 50 of about 1,205,322 (296)

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Preliminary bone histological analysis of Lystrosaurus (Therapsida: Dicynodontia) from the Lower Triassic of North China, and its implication for lifestyle and environments after the end-Permian extinction.

PLoS ONE, 2021
Lystrosaurus represents one of the most successful dicynodonts, a survivor of the end-Permian mass extinction that remained abundant in the Early Triassic, but many aspects of its paleobiology are still controversial.
Fenglu Han, Qi Zhao, Jun Liu
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

The senolytic agent ABT263 ameliorates osteoporosis caused by active vitamin D insufficiency through selective clearance of senescent skeletal cells

Journal of Orthopaedic Translation
Background/Objective: Active vitamin D insufficiency accelerates the development of osteoporosis, with senescent bone cells and the senescence-associated secretory phenotype (SASP) playing crucial roles.
Cuicui Yang, Wanxin Qiao, Qi Xue, David Goltzman, Dengshun Miao, Zhan Dong   +5 more
doaj   +1 more source

The Using of Skeletochronology as a Screening Method for Age Determination of Alpine Newts (Mesotriton Alpestris): a Technical Report

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
Skeletochronology is a widely used method for age determination in amphibians. This method is based mainly on the histological examination of the finger bones.
Peter Makovický, Oldřich Kopecký, Pavol Makovický, Radek Matlach   +3 more
doaj   +1 more source

Pseudogene HSPA7 is a poor prognostic biomarker in Kidney Renal Clear Cell Carcinoma (KIRC) and correlated with immune infiltrates

Cancer Cell International, 2021
Background Pseudogenes played important roles in tumorigenesis, while there are nearly no reports about the expression and roles of HSPA7 in the cancer.
Chunjin Ding, Rundong He, Jinghan Zhang, Zhan Dong, Jun Wu   +4 more
doaj   +1 more source

The effect of allyl isothiocyanate on chondrocyte phenotype is matrix stiffness-dependent: Possible involvement of TRPA1 activation

Frontiers in Molecular Biosciences, 2023
Osteoarthritis (OA) is a chronic joint disease with increasing prevalence. Chondrocytes (CHs) are highly differentiated end-stage cells with a secretory phenotype that keeps the extracellular matrix (ECM) balanced and the cartilage environment stable ...
Hui Che, Zhiqiang Shao, Jiangchen Ding, Hua Gao, Xiangyu Liu, Hailong Chen, Shuangyu Cai, Jiaying Ge, Chengqiang Wang, Jun Wu, Yuefeng Hao   +10 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

HISTOLOGICAL FEATURES OF LARGE BONE ALLOGRAFTS [PDF]

The Journal of Bone and Joint Surgery. British volume, 1996
We performed biopsies during reoperation for minor complications in two active young patients 9 and 19 months after massive bone allograft implantation for bone tumour. The grafts were dead and resorption-apposition activity, when present, was predominantly in subperiosteal areas. Inflammatory infiltration was very seldom found.
F, Gouin, N, Passuti, V, Verriele, J, Delecrin, J V, Bainvel   +4 more
openaire   +2 more sources

A Modified Protocol for Staining of Undecalcified Bone Samples Using Toluidine Blue—A Histological Study in Rabbit Models

Applied Sciences
Undecalcified bone histology is a valuable diagnostic method for studying bone microarchitecture and provides information on bone formation, resorption, and turnover. It has various clinical and research applications.
Stefan Peev, Ivaylo Parushev, Ralitsa Yotsova   +2 more
doaj   +1 more source