Results 41 to 50 of about 283,173 (311)

Evaluation of a New Porcine Bone Graft on the Repair of Surgically Created Critical Bone Defects in Rat Calvaria: Histomorphometric and Microtomographic Study

Journal of Functional Biomaterials, 2022
The aim of this study was to evaluate the use of a new porcine bone graft in rat calvaria bone defects. Critical defects were surgically created in 24 rats that were divided into four experimental groups according to defect filling (n = 6): Control Group
Ytalo Fernandes, Rafael Mantovani, Danilo Reino, Arthur Novaes, Michel Messora, Luiz Gustavo Sousa, Daniela Palioto, Sergio Scombatti de Souza   +7 more
doaj   +1 more source

Importance of geometry of the extracellular matrix in endochondral bone differentiation. [PDF]

, 1984
Subcutaneous implantation of coarse powders (74-420 micron) of demineralized diaphyseal bone matrix resulted in the local differentiation of endochondral bone.
Reddi, AH, Sampath, TK
core   +1 more source

The senolytic agent ABT263 ameliorates osteoporosis caused by active vitamin D insufficiency through selective clearance of senescent skeletal cells

Journal of Orthopaedic Translation
Background/Objective: Active vitamin D insufficiency accelerates the development of osteoporosis, with senescent bone cells and the senescence-associated secretory phenotype (SASP) playing crucial roles.
Cuicui Yang, Wanxin Qiao, Qi Xue, David Goltzman, Dengshun Miao, Zhan Dong   +5 more
doaj   +1 more source

The effect of allyl isothiocyanate on chondrocyte phenotype is matrix stiffness-dependent: Possible involvement of TRPA1 activation

Frontiers in Molecular Biosciences, 2023
Osteoarthritis (OA) is a chronic joint disease with increasing prevalence. Chondrocytes (CHs) are highly differentiated end-stage cells with a secretory phenotype that keeps the extracellular matrix (ECM) balanced and the cartilage environment stable ...
Hui Che, Zhiqiang Shao, Jiangchen Ding, Hua Gao, Xiangyu Liu, Hailong Chen, Shuangyu Cai, Jiaying Ge, Chengqiang Wang, Jun Wu, Yuefeng Hao   +10 more
doaj   +1 more source

Microborings in mid Cretaceous fish teeth [PDF]

, 1999
Fish teeth and other remains from the British Cretaceous contain abundant evidence for post-mortem colonization by endolithic organisms. The borings are here recognised as occurring in three morphotypes, including a flask-shaped form not previously ...
Brett, Bystrov, C. J. Underwood, C. J. Veltkamp, Ennis, Gouget, Martill, Mitchell, Mägdefrau, Owen, S. F. Mitchell, Siverson, Tavernier, Vogel   +13 more
core   +1 more source

Pseudogene HSPA7 is a poor prognostic biomarker in Kidney Renal Clear Cell Carcinoma (KIRC) and correlated with immune infiltrates

Cancer Cell International, 2021
Background Pseudogenes played important roles in tumorigenesis, while there are nearly no reports about the expression and roles of HSPA7 in the cancer.
Chunjin Ding, Rundong He, Jinghan Zhang, Zhan Dong, Jun Wu   +4 more
doaj   +1 more source

Micro-CT Characterization of Human Trabecular Bone in Osteogenesis Imperfecta [PDF]

, 2011
Osteogenesis imperfecta (OI) is a genetic syndrome affecting collagen synthesis and assembly. Its symptoms vary widely but commonly include bone fragility, reduced stature, and bone deformity.
Albert, Carolyne, Harris, Gerald F, Jameson, John, Molthen, Robert C., Smith, Peter   +4 more
core   +2 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Wing bone laminarity in Pterosaurs: insights into torsional adaptations for flight evolution [PDF]

Anais da Academia Brasileira de Ciências
Powered flight has evolved separately in three tetrapod clades: pterosaurs, birds (avian dinosaurs), and bats. To meet the challenges of powered flight, tetrapods acquired structural, mechanical, and physiological adaptations.
ESAÚ VICTOR DE ARAÚJO, JORGE CUBO, MARIANA VALÉRIA DE ARAÚJO SENA, RENAN ALFREDO MACHADO BANTIM, LUIZ CARLOS WEINSCHÜTZ, ALEXANDER WILHELM ARMIN KELLNER, JULIANA MANSO SAYÃO   +6 more
doaj   +1 more source

The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function

Biomolecules, 2020
Autophagy is an evolutionary conserved and highly regulated recycling process of cellular wastes. Having a housekeeping role, autophagy through the digestion of domestic cytosolic organelles, proteins, macromolecules, and pathogens, eliminates ...
Azadeh Montaseri, Claudia Giampietri, Michela Rossi, Anna Riccioli, Andrea Del Fattore, Antonio Filippini   +5 more
doaj   +1 more source