Results 231 to 240 of about 4,190,471 (295)

Osteocytic Pink1/Prkn modulates M6P metabolism and contributes to GC-induced bone loss. [PDF]

J Orthop Translat
Mei J, Zheng Z, Liu D, Zhou J, Gao C, Ma Y, Ding P, Gao J, Huang Y, Yin J.   +9 more
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Zfp462 Is a Key Mediator of Osteoblast Differentiation and Might Contribute to Age-Related Bone Loss. [PDF]

Aging Cell
Kim JM, Kim HK, Moon SA, Kim Y, Lee SH, Yu J, Lee SH, Son WC, Kim JE, Baek IJ, Kim YB, Koh JM.   +11 more
europepmc   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

An Inulin-Type Atractylodes Macrocephala Polysaccharide Alleviates Weightlessness-Induced Bone Loss in Association with the Nrf2/HO-1 Pathway. [PDF]

Nutrients
Wang J, Wang R, Yang F, Wang W, Shen R, Jiang S, Li Q, Yan Q, Li Y, Diao Y, Wei L.   +10 more
europepmc   +1 more source

Coexistence of heterotopic ossification and anterior bone loss after multilevel cervical disc arthroplasty: illustrative case. [PDF]

J Neurosurg Case Lessons
Lin YY, Liu PC, Kuo YH, Huang WC, Wu JC.
europepmc   +1 more source

Bone targeted microenvironment actuated engineered exosomes for precision therapy of IBD associated bone loss. [PDF]

Bioact Mater
Liu J, Wang C, Feng T, Chen S, Ge S, Zhao Y, Chen M, Wang Z, Bao W, Fu P, Wang Z, Kang S, Yin P, Tian Y, Li Y, Pan H.   +15 more
europepmc   +1 more source

Validation of a 3D planning tool for glenoid bone loss evaluation in revision anatomic total shoulder arthroplasty. [PDF]

BMC Musculoskelet Disord
Warnhoff M, Freislederer F, Högl J, Brune D, Lazaridou A, Scheibel M.   +5 more
europepmc   +1 more source

Influence of Gingival Phenotype on Crestal Bone Loss at Implants. [PDF]

J Pharm Bioallied Sci
Azeem M, Patel S, Ranjan R, Verma M, Sri GV, Nagaraju R, Dhanushkodi C, Gautam N.   +7 more
europepmc   +1 more source