Results 111 to 120 of about 1,087,407 (383)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

PB2424: ORAL VERSUS INTRAVENOUS ANTI-CMV PREEMPTIVE THERAPY IN ALLOGENEIC STEM CELL TRANSPLANT PATIENTS WITH CMV REACTIVATION: EXPERIENCE FROM NATIONAL CENTER OF BONE MARROW TRANSPLANTATION, TUNISIA.

HemaSphere, 2023
Rimmel Yosra Kanoun, Nour Ben Adejlil, Jaied Rabeb, Roua Hsasna, Frigui Siwar, Sabrine Mekni, Lamia Torjemane, Ines Turki, Dorra Belloumi, Ouerghi Rihab, Insaf Ben Yaiche, Achour Wafa, Ladeb Saloua, Tarek Ben Othman   +13 more
doaj   +1 more source

Stem Cell Mobilization and Harvesting Failure in Case of Heavily Pretreated Patients

Journal of Interdisciplinary Medicine, 2017
Background: High-dose chemotherapy and autologous stem cell transplantation have become a standard curative treatment in various hematologic malignancies. Many factors can affect the success of mobilization and hematopoietic stem cell harvesting.
Mild Eszter, Lázár Erzsébet, Köpeczi Judit-Beáta, Kakucs Enikő, Găzdac Marius, Pakucs Annamária, Tudor Cezara, Benedek István   +7 more
doaj   +1 more source

Acute lymphoblastic leukemia may develop as a result of rapid transformation of a lymphoblast triggered by repeated bone-remodeling during bone-growth [PDF]

arXiv, 2018
Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are two major forms of leukemia that arise from lymphoid cells (LCs). ALL occurs mostly in children and CLL occurs mainly in old people. However, the Philadelphia-chromosome-positive ALL (Ph+-ALL) and the Ph-like ALL occur in both children and adults.
arxiv  

MR imaging of therapy-induced changes of bone marrow [PDF]

, 2006
MR imaging of bone marrow infiltration by hematologic malignancies provides non-invasive assays of bone marrow cellularity and vascularity to supplement the information provided by bone marrow biopsies. This article will review the MR imaging findings of
A Baur, A Baur, A Baur, A Islam, A Rahmouni, A Rahmouni, A Rahmouni, A Stabler, A Vacca, AA Tountas, AB Fassas, BA Teicher, BC Berg Van de, BC Berg Van de, BC Vande Berg, BD Fletcher, BD Fletcher, BG Durie, BJ Pichler, BR Hoane, BS Coller, C Ricci, CA Perez, CD Pham, CH Bush, CK Wang, D Ballon, D Vanel, DA Turner, DB Smith, DF Yankelevitz, DG Mitchell, DJ Roebuck, DM Plecha, E Seneterre, EG Maghami, EJ Angtuaco, EJ Somer, EL Gerard, EM Delfaut, FE Lecouvet, FE Lecouvet, FE Lecouvet, G Layer, GH Simon, GJ Lieschke, H Gali-Muhtasib, H Hawighorst, H Schirrmeister, HE Daldrup-Link, HE Daldrup-Link, HE Daldrup-Link, Heike E. Daldrup-Link, HH Lien, HH Lien, JK Zawin, JL Montazel, K Lee, K Wasser, L Kornreich, LA Moulopoulos, LA Moulopoulos, LA Moulopoulos, LA Moulopoulos, M Bollow, M Kuliszkiewicz-Janus, MA Dimopoulos, N Ghanem, PL Munk, PL Zinzani, PR Maheshwari, PS Babyn, RD Brunning, S Iida, S Metz, S Nosas-Garcia, S Otake, S Singhal, S Tsunoda, SF Tanner, SG Moore, SK Stevens, SR Smith, Thomas M. Link, TM Moehler, Tobias Henning, V Blomlie, W Negendank, Y Ishibashi   +88 more
core   +2 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Bone Density and Texture from Minimally Post-Processed Knee Radiographs in Subjects with Knee Osteoarthritis [PDF]

arXiv, 2019
Plain radiography is the most common modality to assess the stage of osteoarthritis. Our aims were to assess the relationship of radiography-based bone density and texture between radiographs with minimal and clinical post-processing, and to compare the differences in bone characteristics between controls and subjects with knee osteoarthritis or medial
arxiv  

Reporting guidelines, review of methodological standards, and challenges toward harmonization in bone marrow adiposity research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society [PDF]

, 2020
The interest in bone marrow adiposity (BMA) has increased over the last decade due to its association with, and potential role, in a range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation ...
et al,, Scheller, Erica L, Tratwal, Josefine   +2 more
core   +1 more source

Watch and Wait – Actualities in the Treatment of Chronic Lymphocytic Leukemia

Journal of Interdisciplinary Medicine, 2017
In Western countries, chronic lymphocytic leukemia (CLL) is one of the most diagnosed leukemia types among elderly patients. CLL is described as an indolent lymphoproliferative disorder, characterized by the presence of a high number of small, mature B ...
Bíró Szilárd, Benedek István, Bzduch Árpád, Sándor-Kéri Johanna, Lázár Erzsébet, Benedek István   +5 more
doaj   +1 more source

P1340: RESPONSE RATES AND PROGNOSTIC FACTORS IN ACUTE GASTROINTESTINAL GRAFT-VERSUS-HOST DISEASE

HemaSphere, 2022
J. Freitas, M. Pimenta, E. Couto, P. Coelho, R. Branca, C. Pinho Vaz, L. Leite, A. Campos   +7 more
doaj   +1 more source