Results 111 to 120 of about 2,949,732 (413)

A focus on LBCL patients in partial remission in the CAR-T era

Frontiers in Hematology
The treatment paradigm for large B-cell lymphoma (LBCL) has undergone significant changes in recent years. Patients who fail to achieve a complete response (CR) after first-line therapy (1L) or relapse within 12 months are considered to have a poor ...
Giuseppe Tarantini, Elena Arcuti, Caterina Buquicchio, Vera Carluccio, Gaetano De Santis, Candida Rosaria Germano, Mariangela Leo, Daria Carmela Loconte, Sonia Mallano, Rosanna Maria Miccolis, Teresa Maria Santeramo, Vanda Strafella, Vincenzo Pavone   +12 more
doaj   +1 more source

Leukemia with Plasma Cells — Case Report

Journal of Interdisciplinary Medicine, 2017
Plasma cell leukemia (PCL) is one of the most aggressive monoclonal gammopathies, being characterized by the presence of more than 20% of plasma cells in the peripheral blood and an absolute number of these cells of more than 2×109, with different ...
Benedek István, Benedek István, Köpeczi Judit Beáta, Kéri Johanna Sándor, Pakucs Annamária, Jakab Szende, Lázár Erzsébet   +6 more
doaj   +1 more source

Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis [PDF]

, 2010
Introduction: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease primarily involving the synovium. Evidence in recent years has suggested that the bone marrow (BM) may be involved, and may even be the initiating site of the disease ...
Bellantuono, I., Coulton, L., Croucher, P.I., Gambardella, A., Hughes, D., Kottam, L., Mohanty, S.T., Nicklin, M.J., Wilson, A.G.   +8 more
core   +3 more sources

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

Advanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov, Roberta Gabrieli, Avzal Akbarov, Nigora Nigmatova, Bekhzod Khabilov, Alessandro Schiavi, Martin Schwentenwein, Enrica Verné, Francesco Baino   +8 more
wiley   +1 more source

Human placenta-derived endothelial progenitor cells: an animal-free culture system for efficient expansion

Biological Research
Background Endothelial progenitor cells (EPCs) play a critical role in vasculogenesis and vascular repair, but their clinical application is hindered by challenges such as cell purity, quantity, and reliance on fetal bovine serum (FBS).
Shengnan Yuan, Mengrou Li, Junhao Wang, Wen Ju, Yujin Huang, Yue Li, Haohan Fan, Lingyu Zeng   +7 more
doaj   +1 more source

Watch and Wait – Actualities in the Treatment of Chronic Lymphocytic Leukemia

Journal of Interdisciplinary Medicine, 2017
In Western countries, chronic lymphocytic leukemia (CLL) is one of the most diagnosed leukemia types among elderly patients. CLL is described as an indolent lymphoproliferative disorder, characterized by the presence of a high number of small, mature B ...
Bíró Szilárd, Benedek István, Bzduch Árpád, Sándor-Kéri Johanna, Lázár Erzsébet, Benedek István   +5 more
doaj   +1 more source

EMD273316 & EMD95833, type 4 phosphodiesterase inhibitors, stimulate fibroblastic-colony formation by bone marrow cells via direct inhibition of PDE4 and the induction of endogenous prostaglandin synthesis [PDF]

, 2004
BACKGROUND: Type 4 phosphodiesterase (PDE4) inhibitors have been shown to stimulate bone formation in vivo and to stimulate osteoblastic differentiation in vitro.
Beier, Norbert, Fittschen, Claus, Scutt, Andrew   +2 more
core   +2 more sources

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

PB2446: ALLOGENEIC STEM CELL TRANSPLANTATION WITH GRANULOCYTE COLONY-STIMULATING FACTOR (G-CSF) PRIMED BONE MARROW: PROSPECTIVE STUDY OF THE NATIONAL BONE MARROW TRANSPLANT CENTER IN TUNISIA

HemaSphere, 2023
Rimmel Yosra Kanoun, Ouerghi Rihab, Bizid Inaam, Nour Ben Adejlil, Ines Turki, Lamia Torjemane, Dorra Belloumi, Sabrine Mekni, Insaf Ben Yaiche, Tarek Ben Othman, Ladeb Saloua   +10 more
doaj   +1 more source

Ablation of Proliferating Marrow with 5‐Fluorouracil Allows Partial Purification of Mesenchymal Stem Cells [PDF]

, 2006
The ability to identify and maintain mesenchymal stem cells in vitro is a prerequisite for the ex vivo expansion of cells capable of effecting mesenchymal tissue regeneration. The aim of this investigation was to develop an assay to enrich and ultimately
Krebsbach, Paul H., Song, Junhui, Taichman, Russell S., Wang, Zhuo   +3 more
core   +1 more source