Results 141 to 150 of about 2,858,038 (359)

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

Supervariate Gel Transforms into Various Biominerals in Salt Solutions

Advanced Functional Materials, EarlyView.
It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang, Chong Wang, Yuk‐Tong Cheng, Junda Shen, Yunchen Long, Hongkun Li, Jie Yan, Yang Ren, Xiao Ma, Yufeng Huang, Zhengtao Xu, Jian Lu, Yang Yang Li   +12 more
wiley   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Urethane-Caused Blood and Bone Marrow Changes in Agranulocytosis and Panmyelopathy of the Cat [PDF]

, 1951
S Moeschlin, Andrea Bodmer
openalex   +1 more source

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization.

Circulation Research, 1999
T. Asahara, H. Masuda, Tomono Takahashi, C. Kalka, Christopher Pastore, Marcy Silver, Marianne Kearne, M. Magner, J. Isner   +8 more
semanticscholar   +1 more source

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

Advanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue, Tetsushi Taguchi, Taka‐Aki Asoh, Akihiro Nishiguchi   +3 more
wiley   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

CHANGES IN OUTLYING BONE MARROW ACCOMPANYING A LOCAL INCREASE OF TEMPERATURE WITHIN PHYSIOLOGICAL LIMITS [PDF]

, 1936
Charles Huggins, Berget H. Blocksom
openalex   +1 more source