Results 161 to 170 of about 1,087,407 (383)

Interpenetrating Polymer Network Hydrogels with Tunable Viscoelasticity and Proteolytic Cleavability to Direct Stem Cells In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
A cell‐instructive hydrogel platform is introduced of interpenetrating polymer networks (IPNs) containing sulfated glycosaminoglycan (sGAG) and polyethylene glycol cross‐linked through chemical and physical interactions, respectively. The materials allow for the precise systematic modulation of stiffness, viscoelasticity, and proteolytic cleavability ...
Prannoy Seth   +7 more
wiley   +1 more source

Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS [PDF]

open access: yes, 2011
The LC-ESI-MS was developed and validated for the analysis of imatinib in plasma and bone marrow samples using deuterated imatinib (D(8)-IM) as an internal standard. The biological samples were extracted using Strata-X-C SPE cartridges and separated on C&
Elliott, M.   +4 more
core   +1 more source

Observations on Chimpanzees after Whole-Body Radiation and Homologous Bone Marrow Treatment [PDF]

open access: bronze, 1959
Harvey Rothberg   +3 more
openalex   +1 more source

Bone marrow failure

open access: yesMedicine, 2000
Abstract The term ‘bone marrow failure' encompasses conditions in which there is a primary failure, at the haemopoietic precursor level, to produce one or more of the circulating blood cell lineages. The term usually excludes pancytopenia associated with marrow infiltration (as in acute leukaemia and cytopenias), and those that arise from ...
openaire   +2 more sources

Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik   +2 more
wiley   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

open access: yesAdvanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han   +7 more
wiley   +1 more source

DinoBloom: A Foundation Model for Generalizable Cell Embeddings in Hematology [PDF]

open access: yesarXiv
In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical adoption of computational models has been hampered by the lack of generalization due to large batch effects, small ...
arxiv  

Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario   +2 more
wiley   +1 more source

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