Results 61 to 70 of about 1,570,512 (298)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Bone substitute effect on vascularization and bone remodeling after application of phVEGF165 transfected BMSC [PDF]

, 2012
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming capacities of VEGF transfected bone marrow ...
Beverungen, Mirjam, Wieland, Julia, Michael Fehr, Florian Geiger, Philip Kasten, Mirjam Beverungen, Helga Lorenz, Geiger, Florian, Fehr, Michael, Lorenz, Helga, Julia Wieland, Kasten, Philip   +11 more
core   +1 more source

Protein and gene expression analyses in bone marrow stem cells mediated restoration of myocardium after ischemic insult [PDF]

, 2010
PhDMyocardial Infarction (MI) is caused by occlusion of the coronary artery following atheromatous plaque rupture, the subsequent ischemia in the myocardium leads to myocyte necrosis unless treated quickly. Bone marrow derived stem cell treatment is a
Lee, Kate L
core   +4 more sources

Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review

Case Reports in Gastrointestinal Medicine, 2022
Introduction. Solitary extramedullary plasmacytoma (SEP) is a rare neoplasm that is derived from monoclonal proliferation of plasma cells in the soft tissues or organs arising outside the bone marrow.
Khaoula Khalil, Fatima Ezzahra Lahlimi, Illias Tazi   +2 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Psycholegal Issues in Sibling Bone Marrow Donation

, 1992
The only hope of survival for children with a number of life-threatening illnesses is a successful bone marrow transplant (BMT). Unlike the treatment source for most therapies, the raw material for transplant therapy comes from a human being.
Weisz, Victoria
core   +1 more source

Supersensitive PSA-Monitored neoadjuvant hormone treatment of clinically localized prostate cancer: Effects on positive margins, tumor detection and epithelial cells in bone marrow [PDF]

, 1998
Objective: The present study was done to investigate the effects of supersensitive PSA-controlled inductive treatment on positive margins, detection of tumor and epithelial cells in bone marrow of 101 patients with untreated and clinically localized ...
Köllermann, J., Kaulfuss, U., Spitz, J., Enzmann, Th., Köllermann M. W., Feek, U., Martell, W., Kossiwakis, M.   +7 more
core   +1 more source

Dengue virus infection in hematopoietic stem cell transplant recipients: A case series and comparative literature review from dengue endemic region

SAGE Open Medical Case Reports
This case series describes the wide spectrum of clinical presentation, laboratory findings, and morbidity/mortality associated with dengue fever in hematopoietic stem cell transplant recipients, treated in a dengue endemic region.
Waseem Shahani, Faiqa Fayyaz, Shafaq Abdul Samad, Muhammad Nizamuddin, Madiha Abid, Aisha Jamal, Zainab Ghayas, Ayesha Rafiq, Abdul Hayee, Dilnasheen Safdar, Tasleem Farzana, Uzma Zaidi   +11 more
doaj   +1 more source

Post Autologous Stem Cell Transplantation Complication Management in Case of Malignant Lymphoma Patients

Journal of Interdisciplinary Medicine, 2017
Introduction: Autologous hematopoietic stem cell transplantation (ASCT) represents a standard therapy in the management of hematologic malignancies such as malignant lymphomas and has used for approximately three decades.
Pakucs Annamária, Lázár Erzsébet, Köpeczi Judit Beáta, Kakucs Enikő, Benedek István, Găzdac Marius, Mild Eszter, Tudor Cezara, Benedek István   +8 more
doaj   +1 more source