Results 271 to 280 of about 580,446 (318)

Bone marrow cell separation studies

Experimental Cell Research, 1960
Abstract Differential gradient centrifugation of bone marrow cell suspensions in bovine serum albumin produced layers of mixed cell types. Each layer was capable isologously of promoting survival of heavily irradiated (C57BL × 101)F 1 mice; none was more effective than fresh whole bone marrow.
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Bone Reconstruction with Bone Marrow Stromal Cells

2006
Bone marrow stromal/stem cells (BMSCs) are multipotent adult stem cells and have become the important cell source for cell therapy and engineered tissue repair. Their osteogenic differentiation potential has been well characterized in many in vitro studies.
Wei, Liu, Lei, Cui, Yilin, Cao
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Regulation of Constitutive Bone Marrow Cell Proliferation by Bone Marrow Suppressor Cells

International Archives of Allergy and Immunology, 1984
Bone marrow (BM) cells have previously been shown to suppress specific immune responses of cells from peripheral lymphoid organs. The present report describes a suppressor cell present in normal rabbit BM, which regulated the constitutive proliferation of other BM cells.
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Importance of bone marrow cell dose in bone marrow transplantation

Clinical Transplantation, 1992
The importance of the size of the infused marrow cell dose (MCD) was investigated in 274 patients undergoing allogeneic BMT between 1975 and 1990. Among those, 65 had acute myelogenous leukemia (AML), 79 acute lymphoblastic leukemia (ALL), 58 chronic myelogenous leukemia (CML) and 25 severe aplastic anemia (SAA).
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Bone marrow-derived mesenchymal stem cells

Leukemia & Lymphoma, 2005
Human mesenchymal stem cells (MSCs) contribute to the regeneration of mesenchymal tissues, and are essential in providing support for the growth and differentiation of primitive hemopoietic cells within the bone marrow microenvironment. Techniques are now available to isolate human MSCs and manipulate their expansion in vitro under defined culture ...
Kemp, KC, Hows, J, Donaldson, C
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Bone Marrow-Derived Dendritic Cells

2013
While much is understood about dendritic cells and their role in the immune system, the study of these cells is critical to gain a more complete understanding of their function. Dendritic cell isolation from mouse body tissues can be difficult and the number of cells isolated small.
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Bone-marrow haematopoietic-stem-cell niches

Nature Reviews Immunology, 2006
Adult stem cells hold many promises for future clinical applications and regenerative medicine. The haematopoietic stem cell (HSC) is the best-characterized somatic stem cell so far, but in vitro expansion has been unsuccessful, limiting the future therapeutic potential of these cells. Here we review recent progress in characterizing the composition of
Anne, Wilson, Andreas, Trumpp
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Bone marrow cells regenerate infarcted myocardium

Nature, 2001
Myocardial infarction leads to loss of tissue and impairment of cardiac performance. The remaining myocytes are unable to reconstitute the necrotic tissue, and the post-infarcted heart deteriorates with time. Injury to a target organ is sensed by distant stem cells, which migrate to the site of damage and undergo alternate stem cell differentiation ...
D, Orlic, J, Kajstura, S, Chimenti, I, Jakoniuk, S M, Anderson, B, Li, J, Pickel, R, McKay, B, Nadal-Ginard, D M, Bodine, A, Leri, P, Anversa   +11 more
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Bone marrow-derived cells and hypertension

Expert Review of Cardiovascular Therapy, 2010
Although it is clear that inadequate perfusion underlies most of the organ dysfunction accounting for hypertension-related adverse outcomes, our understanding of the pathophysiologic mechanisms is still evolving. The most important approaches to improving vascular health include reducing injury to the vessel wall and enhancing mechanisms to repair ...
Ki E, Park, Carl J, Pepine
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Thymus Homing Clonogenic Bone Marrow Cells

1985
The thymus plays a major role in guiding the maturation, differentiation and specificity of T cells (1–4), In the adult mouse, the thymus receives small numbers of T cell precursors from the bone marrow and exports to the periphery a large variety of cells that differ by their surface antigens and functions.
S, Ezine, I L, Weissman, R V, Rouse
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