Results 311 to 320 of about 1,176,323 (360)

Bone marrow mesenchymal stem cells

Journal of Cellular Biochemistry, 2009
AbstractFollowing the identification of bone marrow multipotent cells that could adhere to plastic and differentiate along numerous mesenchymal lineages in vitro, a considerable effort has been invested in characterizing and expanding these cells, which are now called “mesenchymal stem cells” (MSCs), in vitro. Over the years, numerous lines of evidence
Masanobu Ohishi, Ernestina Schipani
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VERSATILE STEM CELLS IN BONE MARROW

The Lancet, 1982
The question of whether there is a single pluripotent haemopoietic stem cell or a variety of stem cells each with a capacity for self-replication is still unresolved. Evidence from radiation-chimaeras and from patients with marrow grafts indicates that haemopoietic stem cells are not a homogeneous population.
J. F. Loutit, J. F. Loutit, JanetM. Vaughan, JanetM. Vaughan, M.J. Marshall, M.J. Marshall, N.W. Nisbet, N.W. Nisbet   +7 more
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Bone Marrow-Derived Dendritic Cells

2013
While much is understood about dendritic cells and their role in the immune system, the study of these cells is critical to gain a more complete understanding of their function. Dendritic cell isolation from mouse body tissues can be difficult and the number of cells isolated small.
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Bone Marrow and B Cell Differentiation [PDF]

, 1982
Recent progress in the B lymphocyte field has been rapid. However, the revelations of immunoglobulin gene expression, genesis of antibody diversity and hybridoma technology all serve to highlight outstanding questions conerning the in vivo organization of B lymphocytes and their progenitors.
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The Radiosensitivity of Rat Bone-marrow Cells

International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1970
SummaryThe radiosensitivity of rat bone-marrow cells was determined by the spleen-colony technique. When the marrow cells were irradiated in vivo, the D0 was 97 rads, and the extrapolation number was 5·2. Similar results were obtained after in vitro irradiation: D0 = 94 rads, and extrapolation number = 4·1.
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Bone marrow microenvironment of MPN cells

2021
In this chapter, we will discuss the current knowledge concerning the alterations of the cellular components in the bone marrow niche in Myeloproliferative Neoplasms (MPNs), highlighting the central role of the megakaryocytes in MPN progression, and the extracellular matrix components characterizing the fibrotic bone marrow.
Malara A., Di Buduo C. A., Abbonante V., Balduini A.   +3 more
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Evidence for circulating bone marrow-derived endothelial cells.

Blood, 1998
It has been proposed that hematopoietic and endothelial cells are derived from a common cell, the hemangioblast. In this study, we demonstrate that a subset of CD34(+) cells have the capacity to differentiate into endothelial cells in vitro in the ...
Q. Shi, S. Rafii, Moses Hong-De Wu, E. Wijelath, Cong Yu, A. Ishida, Y. Fujita, Sudesh Kothari, R. Möhle, L. Sauvage, M. A. Moore, R. Storb, W. Hammond   +12 more
semanticscholar   +1 more source

Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow.

Science, 2000
Bone marrow stem cells give rise to a variety of hematopoietic lineages and repopulate the blood throughout adult life. We show that, in a strain of mice incapable of developing cells of the myeloid and lymphoid lineages, transplanted adult bone marrow ...
É. Mezey, K. Chandross, G. Harta, Richard A. Maki, S. Mckercher   +4 more
semanticscholar   +1 more source

Autologous transplantation of bone marrow cells improves damaged heart function.

Circulation, 1999
BACKGROUND Autologous bone marrow cells (BMCs) transplanted into ventricular scar tissue may differentiate into cardiomyocytes and restore myocardial function. This study evaluated cardiomyogenic differentiation of BMCs, their survival in myocardial scar
S. Tomita, Ren-Ke Li, R. Weisel, Donald A. G. Mickle, Eung-Joong Kim, T. Sakai, Z. Jia   +6 more
semanticscholar   +1 more source

T‐CELL DEPLETION OF HUMAN BONE MARROW

International Journal of Immunogenetics, 1989
SUMMARYThe myelo‐ablative effects of high‐dose therapy for refractory cancer can be overcome by the transplantation of bone marrow from an HLA‐matched normal donor. Suitable donors are available for only one patient in three, and even minor disparities at HLA loci can produce graft‐versus‐host disease (GvHD) in transplant recipients.
Virginia Mansour, Adrian P. Gee, M. Weiler   +2 more
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