Results 11 to 20 of about 545,178 (312)
Background: Transfusion-dependent (TDT) β –Thalassemia patients have lower HRQoL than healthy individuals. The impact of Hydroxyurea is always measured with the clinical investigations in terms of laboratory diagnosis.
Affaf Sheikh +4 more
doaj +3 more sources
Bone Marrow Examination in Hodgkin's Disease [PDF]
Bone marrow aspiration and biopsy was performed as part of routine staging in 425 patients with primary Hodgkin's disease. Only seven patients were found to have bone marrow disease by biopsy and only four by aspiration. All these patients had B symptoms and stage III or IV before bone marrow examination.
A F, Abrahamsen +5 more
openaire +2 more sources
Hodgkin's disease in the bone marrow [PDF]
AbstractTumor involvement of the bone marrow in patients with Hodgkin's disease may be suspected in the presence of other manifestations of advanced disease such as fever, lymphopenia, hypoalbuminemia, mixed cellular histologic type, or Stage III or IV disease by other clinical parameters. It occurs more frequently in the older age groups. When anemia,
R B, Weiss, R D, Brunning, B J, Kennedy
openaire +2 more sources
Bone Marrow–on–a–Chip Replicates Hematopoietic Niche Physiology in Vitro [PDF]
Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in live animals.
Collins, James J. +7 more
core +1 more source
Case Report: Invasive Fungal Infection and Daratumumab: A Case Series and Review of Literature
Life expectancy of multiple myeloma (MM) patients has improved in last years due to the advent of anti-CD38 monoclonal antibodies in combination with immunomodulators and proteasome inhibitors.
Francesca Farina +16 more
doaj +1 more source
T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells [PDF]
Background: Human bone marrow and umbilical cord blood are sources of allogeneic hematopoietic stem cells for transplantation, which is a life-saving treatment in a variety of diseases but is burdened by delayed T-cell reconstitution.
De Smedt, Magda +5 more
core +2 more sources
Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]
Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core +2 more sources
Bone marrow manifestations of Hodgkin's disease [PDF]
Bone marrow trephine biopsies were performed on 107 previously untreated patients with Hodgkin's disease (HD). Fifteen patients (14%) exhibited bone marrow involvement. These consisted of two of three patients (67%) with lymphocyte depletion, six of 27 patients (22%) with mixed cellularity, five of 64 patients (8%) with nodular sclerosis, and two who ...
D I, O'Carroll +2 more
openaire +2 more sources
Bone marrow transplantation for autoimmune diseases
Autoimmune diseases afflict approximately 2% of the US population and span virtually every medical specialty. Most patients with autoimmune diseases have a normal life expectancy and are managed conservatively; however, a subset of patients have a progressive disease course associated with significant morbidity and mortality.
R A, Brodsky, B D, Smith
openaire +5 more sources
Stem cell transplantation improves aging-related diseases [PDF]
Aging is a complex process of damage accumulation, and has been viewed as experimentally and medically intractable. The number of patients with age-associated diseases such as type 2 diabetes mellitus (T2DM), osteoporosis, Alzheimer’s disease (AD ...
Ming Li, Susumu Ikehara
core +2 more sources

