Results 91 to 100 of about 309,126 (317)

Twisting the bone marrow stem cell niche

Haematologica, 2018
Hematopoietic stem cells (HSC) are the source of blood cells over the whole lifespan of mammals. HSC locate in the bone marrow microenvironment in the so-called bone marrow stem cell niche. This niche consists of multiple cell types, such as endothelial cells, mesenchymal stem cells (MSC), CXCL12-
Haixia Niu, Jose A. Cancelas
openaire   +4 more sources

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source

A Comparison of Equine Adipose Tissue, Bone Marrow and Peripheral Blood as Sources of Mesenchymal Stem Cells

, 2014
Lameness is a significant cause of wastage in equine athletes, with reportedly 66% days lost from training being contributed to musculoskeletal injuries.
Redmond Hubbard, Amy Louise
core  

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Cross-linking N-succinyl chitosan-oxidated hyaluronic acid-based hydrogel loaded with bone marrow mesenchymal stem cell-derived exosomes induce bone regeneration in cranial defects

Materials & Design
Background: Hydrogel carrying exosomes shows better prospects for bone regeneration. Objective: This work investigated the effect of cross-linking N-succinyl chitosan-oxidated hyaluronic acid-based hydrogel loaded with bone marrow mesenchymal stem cell ...
Xiao-yang Chu, Kai Yang, Xin He, Kai-tao Yu, Ying-yi Luan, Qing-bing He, Ze-lu Li, Yu-lan Xiang, Huaiwen Chen, Yang Zeng, Ya-Zhou Li, Dong-liang Zhang   +11 more
doaj   +1 more source

The role of bone marrow derived cells in cardiac repair

, 2012
PhDCurrent pharmacological therapies fail to address the final end-point of cardiac ischaemia — the death and dysfunction of cardiomyocytes. Advances in stem cell biology have provided hope, for the first time, of addressing this underlying pathology.
Lovell, Matthew J, Lovell, Matthew J.
core  

Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications

Advanced Functional Materials, EarlyView.
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi, Norma Mallegni, Andrea Dorigato, Mario Milazzo   +3 more
wiley   +1 more source

Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin

Nature Communications, 2018
The periosteum, a tissue lining the bone surface, and the bone marrow are known to contain bone-forming cells. Here the authors show that skeletal stem cells reside in the mouse periosteum, and that periosteal cells have common embryonic origins with ...
Oriane Duchamp de Lageneste, Anaïs Julien, Rana Abou-Khalil, Giulia Frangi, Caroline Carvalho, Nicolas Cagnard, Corinne Cordier, Simon J. Conway, Céline Colnot   +8 more
doaj   +1 more source

Noninvasive in vivo tracking of mesenchymal stem cells and evaluation of cell therapeutic effects in a murine model using a clinical 3.0 T MRI

, 2013
Cardiac cell therapy with mesenchymal stem cells (MSCs) represents a promising treatment approach for end-stage heart failure. However, little is known about the underlying mechanisms and the fate of the transplanted cells. The objective of the presented
Neef, Klaus, Drey, Florian, Choi, Yeong-Hoon, Brenkmann, Meike, Tenbrock, Arne, Wahlers, Thorsten, Treskes, Philipp, Wittwer, Thorsten, Liakopoulos, Oliver J, Ewert, Birgit, Bovenschulte, Henning, Stamm, Christof   +11 more
core   +1 more source

Mechanisms of Aging in Bone Marrow Stem Cells

PLoS Biology, 2007
Settling into middle-age typically brings the unpleasant realization that many things don’t work quite like they used to. Spicy foods cause gastric distress. Muscles lose tone and agility. Wounds take longer to heal. Theories of aging abound and genetics clearly plays some role, but there’s little disagreement that the body’s maintenance and repair ...
openaire   +4 more sources