Results 121 to 130 of about 351,718 (359)
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu+16 more
wiley +1 more source
Production of Granulocytic Progeny by Transplanted Bone Marrow in Irradiated Mice [PDF]
Samuel Hellmän, Helen E. Grate
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Oxygen‐releasing immunomodulatory microspheres are used to construct conformal bone organoid units that enhance osteogenesis, angiogenesis, and immune regulation. By integrating BMSCs, macrophages, and CaO₂‐HAp into a SilMA‐based hydrogel platform, this strategy provides sustained oxygen supply and anti‐inflammatory microenvironments, leading to ...
Anfu Deng+12 more
wiley +1 more source
Haematopoietic Chimera in Man After Allogenic (Homologous) Bone-marrow Transplantation [PDF]
G Mathé+4 more
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Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley +1 more source
Modification of Irradiation Injury in the Monkey by Bone Marrow Transplantation [PDF]
Benjamin Crouch, R. R. Overman
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The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan+13 more
wiley +1 more source
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei+11 more
wiley +1 more source
Clinical Report: Conference on Clinical Aspects of Radiation Injury and Transplantation of Bone Marrow and Other Organs [PDF]
C. Gordon Zubrod, Alexander Hollaender
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