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Transfusion and Bone Marrow Transplantation
Transfusion Medicine Reviews, 1988Bone marrow transplantation has prolonged the lives of a significant percentage of patients with a variety of both malignant and nonmalignant disorders. However, the impact of this treatment on a transfusion service is substantial. Large numbers of often specialized blood products are required to support these patients, and the logistics of ...
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A History of Bone Marrow Transplantation
Immunology and Allergy Clinics of North America, 2010The last 40 years has seen the emergence of hematopoietic stem cell transplantation as a therapeutic modality for fatal diseases and as a curative option for individuals born with inherited disorders that carry limited life expectancy and poor quality of life.
M Teresa, de la Morena, Richard A, Gatti
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The Immunogenetics of Bone Marrow Transplantation
Transfusion Medicine Reviews, 1994It is now clear that it is not necessary to use an HLA genotypically identical donor to have a successful marrow transplant. However, it is equally clear that the likelihood of complications increases with each increment in histoincompatibility. The implication is that histocompatibility testing must be of the highest possible precision to choose the ...
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An overview of bone marrow transplantation
Seminars in Oncology Nursing, 1988Abstract BMT has progressed from early isolated attempts in man through controlled animal studies in mice, rats, and dogs to the treatment of choice for some patients. 2 BMT is no longer a treatment of last resort for patients with acute leukemia; rather, it is seen as a viable alternative to conventional maintenance chemotherapy especially for ...
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Reflections on a Bone Marrow Transplant
Annals of Internal Medicine, 2000The author recounts his long journey through bone marrow transplantation and recovery and the new insights he has gained about the doctor–patient relationship.
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Bone marrow transplantation today
Supportive Care in Cancer, 1994Today, bone marrow transplantation (BMT) is an established therapy. This statement is best verified by the number of BMTs performed. Between January 1990 and December 1992, 172 European teams in 26 countries carried out a total of 14,334 transplants. There were 6642 allogeneic transplants: 5513 BMT from an HLA-identical sibling donor, 370 from a non ...
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Hyperuricemia and Bone Marrow Transplantation
2004Blood uric acid levels and purine metabolism are affected in many ways after bone marrow transplantation (BMT). Although BMT is usually performed when patients have a low residual disease burden, a proportion of them are still at risk of tumor lysis syndrome, even with limited disease or after nonmyeloablative conditioning regimens; moreover, an ...
Giorgio Lambertenghi, Deliliers +1 more
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Pediatric bone marrow transplantation
Current Opinion in Pediatrics, 1993Bone marrow transplantation has become well established in the treatment of malignant and nonmalignant disorders. Steady progress continues in improving survival after transplantation, but many problems remain to be solved. Relapsed disease is a major limitation, and new, more intensive preparative regimens are being evaluated in an effort to improve ...
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