Results 21 to 30 of about 672,142 (313)

Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]

open access: yes, 2017
The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover   +6 more
core   +2 more sources

Ptosis as a unique hallmark for autosomal recessive WNT1-associated osteogenesis imperfecta [PDF]

open access: yes, 2019
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder, mainly characterized by bone fragility and low bone mass. Defects in the type I procollagen-encoding genes account for the majority of OI, but increasingly more rare autosomal ...
Elcioglu, Nursel   +8 more
core   +1 more source

Bacterial lipopolysaccharide potentiates type II collagen-induced arthritis in mice

open access: yesMediators of Inflammation, 1992
Collagen-induced arthritis (CIA) is an immunologically relevant animal model of human rheumatoid arthritis. Studies comparing the disease incidence in genetically susceptible male and female DBA/1LacJ mice demonstrated that under low density/low stress ...
Robert G. Caccese   +2 more
doaj   +1 more source

Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles

open access: yesGenome Medicine, 2023
Background Single-cell RNA sequencing (scRNA-seq) provides valuable insights into human islet cell types and their corresponding stable gene expression profiles. However, this approach requires cell dissociation that complicates its utility in vivo.
Randy B. Kang   +9 more
doaj   +1 more source

Transfer RNAs-derived small RNAs and their application potential in multiple diseases

open access: yesFrontiers in Cell and Developmental Biology, 2022
The role of tRNAs is best known as adapter components of translational machinery. According to the central dogma of molecular biology, DNA is transcribed to RNA and in turn is translated into proteins, in which tRNA outstands by its role of the cellular ...
Xiaohua Chu   +7 more
doaj   +1 more source

Protocol for systematic review: peak bone mass pattern in different parts of the world [PDF]

open access: yes, 2015
Copyright: © 2015 Mohammadi Z. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Aghaei Meybodi, Hamidreza   +9 more
core   +2 more sources

Role of cancer stem cells in the development of giant cell tumor of bone

open access: yesCancer Cell International, 2020
The primary bone tumor is usually observed in adolescence age group which has been shown to be part of nearly 20% of the sarcomas known today. Giant cell tumor of bone (GCTB) can be benign as well as malignant tumor which exhibits localized dynamism and ...
Abdul Rouf War   +7 more
doaj   +1 more source

Antimicrobial Biomaterials for the Healing of Infected Bone Tissue: A Systematic Review of Microtomographic Data on Experimental Animal Models

open access: yesJournal of Functional Biomaterials, 2022
Bone tissue infection is a major clinical challenge with high morbidity and a significant healthcare burden. Therapeutic approaches are usually based on systemic antibacterial therapies, despite the potential adverse effects associated with antibiotic ...
Lorena Castro Mariano   +2 more
doaj   +1 more source

Reduced energy availability: implications for bone health in physically active populations [PDF]

open access: yes, 2017
Purpose: The present review critically evaluates existing literature on the effects of short- and long-term low energy availability (EA) on bone metabolism and health in physically active individuals.
Dolan, E   +3 more
core   +1 more source

Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation

open access: yesCells, 2020
Microtubule actin crosslinking factor 1 (MACF1) is a large crosslinker that contributes to cell integrity and cell differentiation. Recent studies show that MACF1 is involved in multiple cellular functions such as neuron development and epidermal ...
Fan Zhao   +18 more
doaj   +1 more source

Home - About - Disclaimer - Privacy