Results 21 to 30 of about 672,142 (313)
Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]
The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover +6 more
core +2 more sources
Ptosis as a unique hallmark for autosomal recessive WNT1-associated osteogenesis imperfecta [PDF]
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder, mainly characterized by bone fragility and low bone mass. Defects in the type I procollagen-encoding genes account for the majority of OI, but increasingly more rare autosomal ...
Elcioglu, Nursel +8 more
core +1 more source
Bacterial lipopolysaccharide potentiates type II collagen-induced arthritis in mice
Collagen-induced arthritis (CIA) is an immunologically relevant animal model of human rheumatoid arthritis. Studies comparing the disease incidence in genetically susceptible male and female DBA/1LacJ mice demonstrated that under low density/low stress ...
Robert G. Caccese +2 more
doaj +1 more source
Background Single-cell RNA sequencing (scRNA-seq) provides valuable insights into human islet cell types and their corresponding stable gene expression profiles. However, this approach requires cell dissociation that complicates its utility in vivo.
Randy B. Kang +9 more
doaj +1 more source
Transfer RNAs-derived small RNAs and their application potential in multiple diseases
The role of tRNAs is best known as adapter components of translational machinery. According to the central dogma of molecular biology, DNA is transcribed to RNA and in turn is translated into proteins, in which tRNA outstands by its role of the cellular ...
Xiaohua Chu +7 more
doaj +1 more source
Protocol for systematic review: peak bone mass pattern in different parts of the world [PDF]
Copyright: © 2015 Mohammadi Z. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Aghaei Meybodi, Hamidreza +9 more
core +2 more sources
Role of cancer stem cells in the development of giant cell tumor of bone
The primary bone tumor is usually observed in adolescence age group which has been shown to be part of nearly 20% of the sarcomas known today. Giant cell tumor of bone (GCTB) can be benign as well as malignant tumor which exhibits localized dynamism and ...
Abdul Rouf War +7 more
doaj +1 more source
Bone tissue infection is a major clinical challenge with high morbidity and a significant healthcare burden. Therapeutic approaches are usually based on systemic antibacterial therapies, despite the potential adverse effects associated with antibiotic ...
Lorena Castro Mariano +2 more
doaj +1 more source
Reduced energy availability: implications for bone health in physically active populations [PDF]
Purpose: The present review critically evaluates existing literature on the effects of short- and long-term low energy availability (EA) on bone metabolism and health in physically active individuals.
Dolan, E +3 more
core +1 more source
Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation
Microtubule actin crosslinking factor 1 (MACF1) is a large crosslinker that contributes to cell integrity and cell differentiation. Recent studies show that MACF1 is involved in multiple cellular functions such as neuron development and epidermal ...
Fan Zhao +18 more
doaj +1 more source

