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A review of spontaneous bone metastases in domestic and laboratory animals [PDF]

open access: yesJournal of Bone Oncology
Bone metastases cause significant morbidity and ultimately death in some human cancer patients. Although experimental animal models of skeletal metastases have been invaluable for investigating the molecular mechanisms of cancer progression and growth in
Shiyu Yuan   +7 more
doaj   +2 more sources

Potential biomarkers for the early detection of bone metastases

open access: yesFrontiers in Oncology, 2023
The clinical manifestations of bone metastases are diversified while many sites remain asymptomatic at early stage. As the early diagnosis method is not perfect and the early symptoms of tumor bone metastasis are not typical, bone metastasis is not easy ...
Yang Hao   +12 more
doaj   +1 more source

A Simple Scoring System Predicting the Survival Time of Patients with Bone Metastases after RT. [PDF]

open access: yesPLoS ONE, 2016
This study aimed to develop a scoring system to predict the survival time of patients with bone metastases after radiation therapy (RT). The scoring system can guide physicians to a better selection of appropriate treatment regimens.The medical records ...
Wen-Yi Zhang   +6 more
doaj   +1 more source

Distribution Features of Skeletal Metastases: A Comparative Study between Pulmonary and Prostate Cancers. [PDF]

open access: yesPLoS ONE, 2015
Bone scintigraphies are widely applied for detecting bone metastases. The aim of this study was to investigate distribution features of bone metastases in pulmonary and prostate cancers.
Changyin Wang, Ying Shen, Shaobo Zhu
doaj   +1 more source

Local surgical complication rates in patients receiving surgery without immediate post-operative radiation therapy for lower extremity bone metastases

open access: yesJournal of Bone Oncology, 2020
Purpose: Pathological metastatic fractures in lower-extremity weight bearing bones often require surgical reconstruction. Post-operative radiation is routinely recommended following surgical reconstruction.
William Pidduck   +5 more
doaj   +1 more source

Incidence of Bone Metastases and Skeletal-Related Events in Patients With EGFR-Mutated NSCLC Treated With Osimertinib

open access: yesJTO Clinical and Research Reports, 2023
Introduction: Bone metastases are frequent in patients with EGFR-mutated (EGFR+) NSCLC. Skeletal-related events (SREs) are common in these patients; however, no data on SRE in osimertinib-treated patients are reported.
Anita J.W. M. Brouns, MD   +8 more
doaj   +1 more source

Advances in Treatment of Patients with Prostate Cancer Bone Metastases

open access: yesZhongliu Fangzhi Yanjiu, 2020
The incidence of bone metastases is relatively high in prostate cancer (PCa) patients. Bone metastases not only cause pain and increase the risk of skeletal related events (SREs), but also have a significant impact on quality of life and shorten the ...
LI Ning, XIAO Guoyou
doaj   +1 more source

Prevalence and prognosis of bone metastases in common solid cancers at initial diagnosis: a population-based study

open access: yesBMJ Open, 2023
Objective Bone is one of the most common target sites for advanced tumours. The objective was to survey the prevalence and prognosis of bone metastases in 12 common solid malignant tumours.Design A retrospective cohort study.Methods A total of 1 425 332 ...
Jing Zhang, Dongfeng Cai, Song Hong
doaj   +1 more source

Association of RANKL and EGFR gene expression with bone metastases in patients with metastatic non-small cell lung cancer

open access: yesFrontiers in Oncology, 2023
IntroductionBone metastases are frequent in patients with non-small cell lung cancer (NSCLC). The receptor activator of Nuclear Factor κB (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) pathway is important in bone metastases development.
Anita J.W.M. Brouns   +19 more
doaj   +1 more source

Risk Factors of Rib Metastases in Nasopharyngeal Carcinoma Patients with Rib 99mTc-MDP Foci on Whole-body Bone Scans

open access: yesZhongliu Fangzhi Yanjiu, 2020
Objective To investigate the correlation of rib 99mTc-MDP foci on whole-body bone scan with clinical variables and rib metastases in nasopharyngeal carcinoma(NPC) patients, and to screen the risk factors of rib metastases.
LI Wei, ZHANG Linqi, LI Wen, ZHANG Rusen
doaj   +1 more source

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