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Significant association of RANKL polymorphisms with bone metastasis among patients with breast cancer [PDF]

open access: yesFrontiers in Oncology
ObjectiveThe purpose of this study was to reveal the genetic correlation of RANKL polymorphisms with bone metastasis in breast cancer patients.MethodsIn this study, 139 bone metastasis patients and 152 no metastasis were included as the case and control ...
Haoyu Lian   +8 more
doaj   +2 more sources

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion [PDF]

open access: yesAdvanced Science
Bone metastasis is a devastating consequence of lung cancer. However, the key metabolic factors that determine the risk of bone metastasis remain unclear. Here, we show that glucose transporter type 3 (SLC2A3) is notably overexpressed by lung cancer bone
Yi Ding   +10 more
doaj   +2 more sources

Bone metastasis pattern of cancer patients with bone metastasis but no visceral metastasis

open access: yesJournal of Bone Oncology, 2019
Background: Bone metastasis of cancer can be a result from systemic blood spreading or vertebral venous plexus spreading. Systemic blood pathway induced bone metastasis can happen in any bone in the body since the spreading is considered to be random ...
Mingyu Zhu   +16 more
doaj   +3 more sources

Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer. [PDF]

open access: yes, 2016
Bone density is controlled by interactions between osteoclasts, which resorb bone, and osteoblasts, which deposit it. The semaphorins and their receptors, the plexins, originally shown to function in the immune system and to provide chemotactic cues for ...
Basile, John R   +6 more
core   +24 more sources

Risk factors of bone metastasis in lung adenocarcinoma [PDF]

open access: yesBMC Pulmonary Medicine
Objective To investigate the risk factors of bone metastasis in lung adenocarcinoma and construct a risk prediction model. Methods Patients with newly diagnosed primary lung adenocarcinoma admitted to our hospital between 1 March 2018 and 1 March 2023 ...
Zhongnian Cao   +8 more
doaj   +2 more sources

Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models. [PDF]

open access: yes, 2015
Bone metastasis is a frequent occurrence in prostate cancer patients and often is lethal. Zoledronic acid (ZOL) is often used for bone metastasis with limited efficacy.
Bouvet, Michael   +9 more
core   +10 more sources

A Predictive Nomogram for Early Death in Pheochromocytoma and Paraganglioma

open access: yesFrontiers in Oncology, 2022
BackgroundPheochromocytoma (PHEO) and paraganglioma (PGL) are relatively rare neuroendocrine tumors. The factors affecting patients with early death remain poorly defined. We aimed to study the demographic and clinicopathologic pattern and to develop and
Huiyang Li   +17 more
doaj   +1 more source

Association between malnutrition and leucopenia in patients with osteosarcoma

open access: yesFrontiers in Nutrition, 2022
Background and aimLeucopenia (LP) greatly limits the efficacy of chemotherapy in osteosarcoma patients. This study aimed to evaluate the nutritional status of osteosarcoma patients before chemotherapy, assess the risk of LP during the perichemotherapy ...
Haixiao Wu   +21 more
doaj   +1 more source

The 100 most cited papers on bone metastasis: A bibliometric analysis

open access: yesJournal of Bone Oncology, 2022
Background: Over the past few decades, a vast number of articles focused on bone metastasis have been published. Bibliometric analysis is helpful to determine the qualities and characteristics and to reveal the influential articles in this field. Methods:
Huiyang Li   +9 more
doaj   +1 more source

Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions

open access: yesnpj Precision Oncology, 2021
Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically relevant kinase fusions in Chinese lung cancer and to explore rare
Binghao Li   +17 more
doaj   +1 more source

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