Results 41 to 50 of about 256,782 (261)

Formation of pre-metastatic bone niche in prostate cancer and regulation of traditional chinese medicine

Frontiers in Pharmacology, 2022
Prostate cancer with bone metastasis has a high cancer-specific mortality. Thus, it is essential to delineate the mechanism of bone metastasis. Pre-metastatic niche (PMN) is a concept in tumor metastasis, which is characterized by tumor-secreted factors,
Chiwei Chen, Renlun Huang, Jianfu Zhou, Lang Guo, Songtao Xiang   +4 more
doaj   +1 more source

Relationship of Tumor Markers and Hilar Lymph Nodes with Bone Metastasis of Whole Body Bone Imaging in Lung Adenocarcinoma

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the relationship between tumor markers of lung cancer and bone metastasis of whole body bone imaging in lung adenocarcinoma. Methods The whole body bone imaging of 278 patients diagnosed as lung adenocarcinoma in our hospital was
CAO Zhongnian, ZHENG Rong, WEI Zhengmao, HONG Hao, GUAN Zhimei, LI Yuhuan   +5 more
doaj   +1 more source

Application of unilateral biportal endoscopy in minimally invasive treatment of non-aggressive spinal benign tumors: technical note and preliminary clinical study

Frontiers in Surgery
ObjectiveTo introduce the technical protocol of unilateral biportal endoscopy (UBE) in the treatment of patients with non-aggressive spinal benign tumors and evaluate its clinical efficacy and safety.MethodsA retrospective analysis was conducted on 14 ...
Qiang Ren, Qiang Ren, Liang-Jie He, Liang-Jie He, Qi-Chang Li, Qi-Chang Li, Jia-Nan Zhang, Jia-Nan Zhang, Shi-Chang Dai, Shi-Chang Dai, Wen-Ge He, Wen-Ge He, Liang Chen, Liang Chen   +13 more
doaj   +1 more source

MAZ promotes prostate cancer bone metastasis through transcriptionally activating the KRas-dependent RalGEFs pathway

Journal of Experimental & Clinical Cancer Research, 2019
Background Clinically, prostate cancer (PCa) exhibits a high avidity to metastasize to bone. Myc-associated zinc-finger protein (MAZ) is a well-documented oncogene involved in the progression and metastasis of multiple cancer types, even in PCa. However,
Qing Yang, Chuandong Lang, Zhengquan Wu, Yuhu Dai, Shaofu He, Wei Guo, Shuai Huang, Hong Du, Dong Ren, Xinsheng Peng   +9 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

miR-204-5p Represses Bone Metastasis via Inactivating NF-κB Signaling in Prostate Cancer

Molecular Therapy: Nucleic Acids, 2019
The prime issue derived from prostate cancer (PCa) is its high prevalence to metastasize to bone. MicroRNA-204-5p (miR-204-5p) has been reported to be involved in the development and metastasis in a variety of cancers.
Qingde Wa, Sheng Huang, Jincheng Pan, Yubo Tang, Shaofu He, Xiaodong Fu, Xinsheng Peng, Xiao Chen, Chunxiao Yang, Dong Ren, Yan Huang, Zhuangwen Liao, Shuai Huang, Changye Zou   +13 more
doaj   +1 more source

Restoring Tissue Homeostasis at Metastatic Sites: A Focus on Extracellular Vesicles in Bone Metastasis

Frontiers in Oncology, 2021
Bone is the most common site of cancer metastasis and the spread of cancer cells to the bone is associated with poor prognosis, pain, increased risk of fractures, and hypercalcemia.
Domenica Giannandrea, Valentina Citro, Elena Lesma, Monica Bignotto, Natalia Platonova, Raffaella Chiaramonte   +5 more
doaj   +1 more source