Results 21 to 30 of about 264,729 (304)
BMC Cancer, 2023 Background The aim of study was to evaluate survival outcome and limb function in cancer patients with proximal limbs metastasis. Associated factors on survival outcome and limb function were identified.
Chao Zhang +9 more
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Novel Methods of Targeting IL-1 Signalling for the Treatment of Breast Cancer Bone Metastasis [PDF]
, 2022 Breast cancer bone metastasis is currently incurable. Evidence suggests that inhibiting IL-1 signalling with the IL1R antagonist, Anakinra, or the IL1β antibody, Canakinumab, prevents metastasis and almost eliminates breast cancer growth in the bone.
Marwa A. Alsharif +22 more
core +1 more source
Investigating the contribution of the unfolded protein response to prostate cancer bone metastasis
, 2022 The majority of deaths from prostate cancer (PCa) arise following metastasis, particularly to the skeleton. ER stress and the unfolded protein response (UPR) promote primary PCa, however, the contribution of the UPR to PCa bone metastasis remains unknown.
Kaya, Zeynep
core +1 more source
Basement membrane-rich Organoids with functional human blood vessels are permissive niches for human breast cancer metastasis [PDF]
, 2013 Metastasic breast cancer is the leading cause of death by malignancy in women worldwide. Tumor metastasis is a multistep process encompassing local invasion of cancer cells at primary tumor site, intravasation into the blood vessel, survival in systemic ...
David Sánchez-Martín (264504) +39 more
core +1 more source
Immune microenvironment in breast cancer bone metastasis
, 2021 Bone metastasis is the major cause of death in breast cancer. However, the underlying mechanisms of bone metastasis progression are still largely unknown.
Ma, Ruoyu
core +1 more source
Current Oncology, 2022 The incidence of metastatic bone disease is increasing, as patients with cancer are living longer [...]
openaire +3 more sources
Zhongliu Fangzhi Yanjiu, 2022 Objective To evaluate the value of the systemic immune-inflammatory index (SII), CEA, Cyfra21-1, and NSE in predicting and diagnosing bone metastasis of lung cancer. Methods The clinical data of 618 patients with lung cancer were retrospectively analyzed.
TANG Min, LI Guixiang
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Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis [PDF]
Endocrinology and Metabolism, 2016 Bone metastasis is a frequent occurrence in breast cancer, affecting more than 70% of late stage cancer patients with severe complications such as fracture, bone pain, and hypercalcemia.
Yibin Kang
doaj +1 more source
Journal of Visualized Experiments, 2012 Bone metastases are a common occurrence in several malignancies, including breast, prostate, and lung. Once established in bone, tumors are responsible for significant morbidity and mortality. Thus, there is a significant need to understand the molecular mechanisms controlling the establishment, growth and activity of tumors in bone.
J Preston, Campbell +4 more
openaire +3 more sources
BMC Cancer, 2021 Background Early screening and intervention therapies are crucial to improve the prognosis of hepatocellular carcinoma (HCC) patients with bone metastasis. We aimed to identify serum lncRNA as a prediction biomarker in HCC bone metastasis.
Li Zhang +6 more
doaj +1 more source