Results 11 to 20 of about 372,366 (297)

Non-cancer Causes of Death Following Initial Synchronous Bone Metastasis in Cancer Patients

Frontiers in Medicine, 2022
PurposeTo investigate the non-cancer causes of death (COD) in cancer patients with synchronous bone metastasis (BM) that is based on the Surveillance, Epidemiology, and End Results (SEER) database.MethodsThe retrospective cohort study included malignant ...
Yao Xu, Yao Xu, Basel Abdelazeem, Basel Abdelazeem, Kirellos Said Abbas, Yile Lin, Yile Lin, Haixiao Wu, Haixiao Wu, Fei Zhou, Fei Zhou, Karl Peltzer, Vladimir P. Chekhonin, Vladimir P. Chekhonin, Shu Li, Shu Li, Huiyang Li, Huiyang Li, Wenjuan Ma, Wenjuan Ma, Chao Zhang, Chao Zhang   +21 more
doaj   +1 more source

Ten-year retrospect of the investigation of proximal limbs metastasis in cancer: a multi-center study on survival outcome, limb function status and surgical procedures analysis

BMC Cancer, 2023
Background The aim of study was to evaluate survival outcome and limb function in cancer patients with proximal limbs metastasis. Associated factors on survival outcome and limb function were identified.
Chao Zhang, Jun Wang, Haixiao Wu, Yile Lin, Vladimir P. Chekhonin, Karl Peltzer, Artem V. Bukharov, Andrey D. Kaprin, Xu Guo, Zheng Liu   +9 more
doaj   +1 more source

Cellular and molecular mediators of bone metastatic lesions [PDF]

, 2018
Bone is the preferential site of metastasis for breast and prostate tumor. Cancer cells establish a tight relationship with the host tissue, secreting factors that stimulate or inhibit bone cells, receiving signals generated from the bone remodeling ...
Battafarano, Giulia, Del Fattore, Andrea, Marampon, Francesco, Rossi, Michela   +3 more
core   +5 more sources

Insights into immuno-oncology drug development landscape with focus on bone metastasis

Frontiers in Immunology, 2023
Bone is among the main sites of metastasis in breast, prostate and other major cancers. Bone metastases remain incurable causing high mortality, severe skeletal-related effects and decreased quality of life.
Tiina E. Kähkönen, Jussi M. Halleen, Gary MacRitchie, Ronnie M. Andersson, Jenni Bernoulli   +4 more
doaj   +1 more source

Clinicomics-guided distant metastasis prediction in breast cancer via artificial intelligence

BMC Cancer, 2023
Background Breast cancer has become the most common malignant tumour worldwide. Distant metastasis is one of the leading causes of breast cancer-related death.
Chao Zhang, Lisha Qi, Jun Cai, Haixiao Wu, Yao Xu, Yile Lin, Zhijun Li, Vladimir P. Chekhonin, Karl Peltzer, Manqing Cao, Zhuming Yin, Xin Wang, Wenjuan Ma   +12 more
doaj   +1 more source

Transcriptomic Response to Acidosis Reveals Its Contribution to Bone Metastasis in Breast Cancer Cells

Cells, 2022
Bone is the most common site of metastasis in breast cancer. Metastasis is promoted by acidosis, which is associated with osteoporosis. To investigate how acidosis could promote bone metastasis, we compared differentially expressed genes (DEGs) in MDA-MB-
Ana Sayuri Yamagata, Paula Paccielli Freire, Nícolas Jones Villarinho, Ramon Handerson Gomes Teles, Kelliton José Mendonça Francisco, Ruy Gastaldoni Jaeger, Vanessa Morais Freitas   +6 more
doaj   +1 more source

The immunohistochemical expression of leptin in lymph node metastasis from laryngeal squamous cell carcinoma (SCC) [PDF]

, 2020
Introduction: Leptin is a proteohormone produced predominantly by white adipocytes and primarily known for its key role in the control of food intake and sense of satiety.
D'Alessi S, Ferrara S, Florena AM, Galletti B, Galletti F, Gargano R, Greco G, Verro .   +7 more
core   +1 more source

MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2. [PDF]

, 2017
MicroRNAs (miRNAs) have emerged as key players in cancer progression and metastatic initiation yet their importance in regulating prostate cancer (PCa) metastasis to bone has begun to be appreciated.
Colden, Melissa, Dahiya, Priya V, Dahiya, Rajvir, Dar, Altaf A, Majid, Shahana, Saini, Sharanjot, Shahryari, Varahram, Stein, Gary, Tanaka, Yuichiro, Yamamura, Soichiro   +9 more
core   +2 more sources

Osteocytes and Bone Metastasis [PDF]

Frontiers in Endocrinology, 2020
Bone is the most frequent site of breast cancer and prostate cancer metastasis, and one of the most common sites of metastasis for many solid tumors. Once cancer cells colonize in the bone, it imposes a major clinical challenge for the treatment of the disease, and fatality rates increase drastically.
Manuel A. Riquelme, Eduardo R. Cardenas, Jean X. Jiang   +2 more
openaire   +3 more sources

New insight into long non-coding RNAs associated with bone metastasis of breast cancer based on an integrated analysis

Cancer Cell International, 2021
Background Bone is the most common site of metastatic breast cancer, and it is a leading cause of breast cancer-related death. This study aimed to explore bone metastasis-related long non-coding RNAs (lncRNAs) in breast cancer. Methods Four mRNA datasets
Yu Zhang, Xiaofeng Huang, Jin Liu, Guo Chen, Chengjun Liu, Sen Zhang, Jiaxin Li   +6 more
doaj   +1 more source