Results 11 to 20 of about 1,181,357 (307)
Biology of Bone Metastases [PDF]
Background Bone metastases cause morbidity and mortality in multiple malignancies. In addition to portending a dire prognosis, bone metastases cause bone pain, fractures, hypercalcemia, spinal cord compression, and other nerve compression syndromes ...
Richard L. Theriault +1 more
core +3 more sources
The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer.
Coleman, Robert E. +4 more
core +3 more sources
Editorial: Bone Metastases [PDF]
No abstract ...
Valenti, Maria Teresa +3 more
openaire +4 more sources
Denise A Yardley1,2 1Sarah Cannon Research Institute, Nashville, TN, USA; 2Tennessee Oncology, Nashville, TN, USA Abstract: There is a high risk for bone loss and skeletal-related events, including bone metastases, in postmenopausal women with hormone ...
Yardley DA
doaj +1 more source
Bone metastases of the hand [PDF]
Introduction The aim of this study was to identify patients with malignant hand lesions, establish the proportions of those that were metastases and review their clinical course. Methods A retrospective search of a prospective tumour database was carried out to identify all patients treated at our unit with hand metastases.
G, Morris +6 more
openaire +2 more sources
Value of procollagen type I aminoterminal propeptide in women with breast cancer with regard to metastases [PDF]
Background. The aim of this study was to show the importance of the bone marker procollagen type 1 aminoterminal propeptide (P1NP) in detecting bone metastases in women suffering from breast cancer.
Oremek, Gerhard +3 more
core +1 more source
Bone Microenvironment‐Suppressed T Cells Increase Osteoclast Formation and Osteolytic Bone Metastases in Mice [PDF]
Immunotherapies use components of the immune system, such as T cells, to fight cancer cells, and are changing cancer treatment, causing durable responses in some patients.
Felipe Olvera +24 more
core +1 more source
Late widespread skeletal metastases from myxoid liposarcoma detected by MRI only [PDF]
Background Myxoid liposarcoma is the second most commonly occurring sub-type of liposarcomas. In contrast to other soft tissue sarcomas, it is known to have a tendency to spread toward extrapulmonary sites, such as soft tissues, retroperitoneum, and the
Lee A David +20 more
core +1 more source
Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]
Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Walz, A. +5 more
core +1 more source
Pathophysiology of bone metastases [PDF]
Normal bone remodeling maintains an appropriate balance between the action of osteoclasts (bone-resorbing cells) and osteoblasts (bone-forming cells). Skeletal malignancies, including bone metastases, disrupt the OPG-RANKL-RANK signal transduction pathway and promote enhanced osteoclast formation, thereby accelerating bone resorption and inducing bone ...
James R, Berenson +2 more
openaire +2 more sources

