Results 181 to 190 of about 255,505 (337)

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Bone Metastases of Breast Cancer in the Skull Base: An Unusual Metastatic Spread. [PDF]

Cureus
Beja MS, Marques J, Cardoso VS, Sidiropoulou Z.   +3 more
europepmc   +1 more source

Denosumab for Prevention of Skeletal-Related Events in Patients With Bone Metastases From Solid Tumors: Incremental Benefit, Debatable Value [PDF]

, 2011
Howard West
openalex   +1 more source

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

Analysis of the clinical characteristics of bone metastases after pheochromocytoma/paraganglioma surgery. [PDF]

Front Endocrinol (Lausanne)
Li L, Gao H, Shao Y, Zhu X.
europepmc   +1 more source

Biomimetic Organic Nanozyme as Tumor Vaccines for Targeted Suppression of Ammonia‐Induced T Lymphocyte Death to Augment Breast Cancer Immunotherapy

Advanced Science, EarlyView.
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo, Deyi Yang, Mingpu Yang, Jue Wang, Dingfeng Zhang, Daoming Zhu, Qingyong Xu, Yanni Song   +7 more
wiley   +1 more source

Disseminated tuberculosis without pulmonary involvement mimicking multiple bone metastases. [PDF]

Korean J Intern Med
Lee HJ, Byun SJ, Kim SH.
europepmc   +1 more source

Psoas muscle area is an independent survival prognosticator in patients undergoing surgery for long‐bone metastases [PDF]

Chia‐Che Lee, Ting‐En Tseng, Ruey‐Feng Chang, Hung‐Kuan Yen, Yu‐An Chen, Yu‐Yung Chen, Chih‐Horng Wu, Ming‐Hsiao Hu, Mao‐Hsu Yen, Michiel E. R. Bongers, Olivier Q. Groot, Cheng‐Yo Lai, Wei‐Hsin Lin   +12 more
openalex   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Bone metastases in pheochromocytomas and paragangliomas: a narrative review of presentation, diagnosis and management. [PDF]

Front Endocrinol (Lausanne)
Contreras-Saldarriaga JE, Loaiza-Alzate M.   +1 more
europepmc   +1 more source