Results 191 to 200 of about 2,076,755 (337)

Targeting the Hyperglycemic Pre‐Metastatic Niche to Prevent Breast Cancer Bone Metastasis: Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
Abstract The recent pioneering study by Ye et al. (Adv Sci. 2025;12(37):e0504924) provides compelling evidence that systemic hyperglycemia orchestrates a pre‐metastatic niche (PMN) in bone, promoting breast cancer metastasis and identifying Receptor for Advanced Glycation End‐products (RAGE) inhibition as a viable therapeutic strategy.
DuJiang Yang, Jiexiang Yang, GuoYou Wang
wiley   +1 more source

Recent Progress in Mechanoluminescence for Multi‐Dimensional Stress Monitoring

open access: yesAdvanced Science, EarlyView.
Multi‐dimensional stress visualization technology (0D point detection, 1D linear distribution, 2D planar imaging, 3D volume reconstruction) has become a focus of attention in the field of stress sensing. The transition from “points” to “multi‐dimensional spatial fields” facilitates real‐time, in situ, and high‐resolution visualization of stress ...
Xiuxia Yang   +3 more
wiley   +1 more source

Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial.

open access: yesJournal of Clinical Oncology, 2018
B. Escudier   +16 more
semanticscholar   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

Management of breakthrough cancer pain (BTcP) in patients with bone metastases of solid tumors [PDF]

open access: bronze, 2016
Gian Paolo Spinelli   +16 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

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