Results 231 to 240 of about 255,505 (337)

Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis

Advanced Science, EarlyView.
The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley   +1 more source

Multiple Bone Metastases From Non-Muscle Invasive Bladder Cancer Responding to Combination Therapy With Enfortumab Vedotin and Pembrolizumab: A Case Report. [PDF]

IJU Case Rep
Kanemoto S, Yamamoto S, Hino K, Tsuboi K, Kakizaki M, Nishiyama Y, Fukata S, Arata R, Inoue K, Ono N.   +9 more
europepmc   +1 more source

Case of Carcinoma of the Stomach with Metastases in the Bone-Marrow, and a Blood Picture Suggestive of Pernicious Anæmia.

, 1910
Archibald W Harrington, John H. Teacher
openalex   +1 more source

Prostate-specific antigen and risk of bone metastases in west Africans with prostate cancer

, 2019
Yaw Ampem Amoako, Emmanuel Nii Boye Hammond, Awo Assasie-Gyimah, Dennis Odai Laryea, Alfred O. Ankrah, George Amoah   +5 more
openalex   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

Validation of nine prognostic models in patients with bone metastases undergoing surgery. [PDF]

J Orthop Surg Res
Smolle MA, Elmer P, Wenzl FA, Leitner L, Ferlic P, Scheipl S, Sadoghi P, Leithner A.   +7 more
europepmc   +1 more source

Treatment of metastatic spinal lesions with a navigational bipolar radiofrequency ablation device: A multicenter retrospective study [PDF]

, 2014
Anchala, Praveen R, Brook, Allan, Coldwell, Douglass M, Friedman, Michael V, Georgy, Bassem A, Hillen, Travis J, Irving, Winston D, Jennings, Jack W, Tran, Nam D, Vrionis, Frank D   +9 more
core   +1 more source

CXC Chemokine‐Driven Vascular Reprogramming: Modulating Tumor Vasculature to Boost Therapeutic Response

Advanced Science, EarlyView.
Tumor vascular remodeling is discussed from a chemokine‐centered perspective. This review summarizes the bidirectional, temporal, and tissue‐specific roles of CXC chemokines in regulating vascular function and immune accessibility. A functional vascular normalization score is introduced as a conceptual framework to integrate dynamic vascular and immune
Hongdan Chen, Yinde Huang, Juntong Wu, Ziying Yi, Yao Li, Zeyu Yang, Fan Zhang, Chong Li   +7 more
wiley   +1 more source

Denosumab usage is associated with better overall survival of patients with lung cancer and bone metastases: a retrospective cohort study. [PDF]

BMJ Open Respir Res
Yu CC, Lee HS, Wu JT, Huang CC, Chen JY.
europepmc   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source