Results 251 to 260 of about 2,076,755 (337)

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Efficacy, safety and economy of denosumab and zoledronic acid in the treatment of bone metastases of solid tumors and multiple myeloma: a systematic review and meta-analysis. [PDF]

Front Oncol
Zhong L, Chen W, Zheng D, Cao Y, Zhu L, Zhu Z, Liao L, Dai L, Wang X, Zeng Z.   +9 more
europepmc   +1 more source

Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer

British Journal of Clinical Pharmacology, EarlyView.
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog, Niven Mehra, Anouk van Kleef, Diederik M. Somford, Inge M. van Oort, Alex L. T. Imholz, Paul Hamberg, Nielka P. van Erp, Emmy Boerrigter   +8 more
wiley   +1 more source

Risk Stratification for the Prediction of Skeletal-Related Events in Patients With Bone Metastases From Non-small Cell Lung Cancer. [PDF]

Cureus
Sakamoto Y, Nakata E, Hamada M, Katayama Y, Sugihara S, Ozaki T.   +5 more
europepmc   +1 more source

Rapid bone repair in a patient with lung cancer metastases to the spine using a novel herbal medicine: A case report

, 2016
Rong Pu, Qianhong Zhao, Zhimei Li, Lingyan Zhang, Xiaolu Luo, Yangji Zeren, Yu Cui, Xianyong Li   +7 more
openalex   +2 more sources

Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat

British Journal of Clinical Pharmacology, EarlyView.
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton, Nielka P. van Erp, Annenienke C. van de Ven, Janneke E. W. Walraven, Loek A. W. de Jong   +4 more
wiley   +1 more source

Sarcopenia as a Potential Risk Factor for Denosumab-Related Osteonecrosis of the Jaw in Asian Prostate Cancer Patients with Bone Metastases. [PDF]

Diagnostics (Basel)
Mizushima S, Watanabe D, Yanagida K, Kawae N, Goto K, Takagi T, Kajihara H, Mizushima A.   +7 more
europepmc   +1 more source

Diagnostic test accuracy study of ¹⁸F-sodium fluoride PET/CT, ^99mTc-labelled diphosphonate SPECT/CT, and planar bone scintigraphy for diagnosis of bone metastases in newly diagnosed, high-risk prostate cancer.

, 2017
Randi F. Fonager, Helle D. Zacho, Niels Christian Langkilde, Joan Fledelius, June Anita Ejlersen, Christian Haarmark, Helle Westergren Hendel, Mine Benedicte Lange, Mads Ryø Jochumsen, Jesper Mortensen, Lars J. Petersen   +10 more
openalex   +1 more source

Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles, Jyotirmoy Roy, Michael D. Brooks, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea, Sophia M. Orbach   +6 more
wiley   +1 more source

Establishment and validation of a nomogram model for predicting early death in patients with endometrial cancer bone metastases. [PDF]

Front Oncol
Tang Q, Sun Y, Gao Y.
europepmc   +1 more source