Results 121 to 130 of about 381,513 (352)

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Fractionated radiotherapy initiated at the early stage of bone metastasis is effective to prolong survival in mouse model

open access: yesCancer Biology & Therapy
Background and purpose Bone metastasis is common for breast cancer and associated with poor prognosis. Currently, radiotherapy (RT) serves as the standard treatment for patients exhibiting symptoms of bone metastasis to alleviate pain.
Yun Zhang   +8 more
doaj   +1 more source

Risk Factors of Non-small Cell Lung Cancer with Bone Metastasis after Therapy

open access: yesChinese Journal of Lung Cancer, 2018
Background and objective Lung cancer is the leading cause of cancer-related deaths, patients with non-small cell lung cancer (NSCLC) usually have distant metastases, such as bone metastasis, brain metastasis, and lung metastasis.
Yuanshan YAO   +3 more
doaj   +1 more source

A glance at imaging bladder cancer. [PDF]

open access: yes, 2018
Purpose: Early and accurate diagnosis of Bladder cancer (BCa) will contribute extensively to the management of the disease. The purpose of this review was to briefly describe the conventional imaging methods and other novel imaging modalities used for ...
Halpern, Ethan J.   +4 more
core   +1 more source

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

open access: yesAdvanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei   +5 more
wiley   +1 more source

Bone Marrow Adipocyte: An Intimate Partner With Tumor Cells in Bone Metastasis

open access: yesFrontiers in Endocrinology, 2018
The high incidences of bone metastasis in patients with breast cancer, prostate cancer and lung cancer still remains a puzzling issue. The “seeds and soil” hypothesis suggested that bone marrow (soil) may provide a favorable “niche” for tumor cells (seed)
Guojing Luo, Yuedong He, Xijie Yu
doaj   +1 more source

Supplementary Figure 1 from Elevated TNFR1 and Serotonin in Bone Metastasis Are Correlated with Poor Survival following Bone Metastasis Diagnosis for Both Carcinoma and Sarcoma Primary Tumors [PDF]

open access: gold, 2023
Antonella Chiechi   +9 more
openalex   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

open access: yesAdvanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang   +15 more
wiley   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

open access: yesAdvanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu   +15 more
wiley   +1 more source

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