Results 201 to 210 of about 381,513 (352)

Targeting TUBB3 Suppresses Anoikis Resistance and Bone Metastasis in Prostate Cancer (Adv. Healthcare Mater. 28/2024) [PDF]

Bingqi Dong, Yanlun Gu, Xiaojiao Sun, Xin Wang, Ying Zhou, Zhuona Rong, Jixin Zhang, Xuedong Shi, Zhuo Zhang, He Xu, Lin Chen, Qingqing Xiong, Xiaocong Pang, Yimin Cui   +13 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Recognition of the novel items for prediction of bone metastasis in colorectal cancer. [PDF]

Front Oncol
Chen M, Wang X, Bai S, Lan N, Wang J, Chen Y, Gao Y, Wang W, Shang X, Jiao M, Zhang X, Li W, Wu F, Liu W, Hu F, Chen L, Ren J.   +16 more
europepmc   +1 more source

Bone metastasis of the subtrochanteric femur shaft

, 2012
Roberto Schubert
openalex   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Aberrant lipid metabolism reshapes the immune landscape in bone metastasis of nasopharyngeal carcinoma. [PDF]

J Immunother Cancer
Feng Y, Wang H, Zhu Z, Deng W, He X, Yao Y, Song M, Peng X, Lin Y, Cai L.   +9 more
europepmc   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Hypercalcemia associated with relapsed medulloblastoma due to bone metastasis: illustrative case. [PDF]

J Neurosurg Case Lessons
Ito R, Kanamori M, Shimoda Y, Irie M, Niizuma H, Watanabe H, Watanabe M, Kanemura Y, Kikuchi A, Endo H.   +9 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Concurrent pathologic femoral shaft fracture in bone metastasis and acute myocardial infarction: a case report. [PDF]

J Surg Case Rep
Katsuyama Y, Nakamura S, Sasaki K, Saito T, Takahashi K.   +4 more
europepmc   +1 more source