Results 71 to 80 of about 21,763 (267)

A novel mechanical parameter to quantify the microarchitecture effect on apparent modulus of trabecular bone: A computational analysis of ineffective bone mass

, 2020
Background: One of the characteristics of osteoporotic bone is the deterioration of trabecular microarchitecture. Previous studies have shown microarchitecture alone can vary the apparent modulus of trabecular bone significantly independent of bone ...
Wong, TM, Zhang, T, Sun, T, Zu, H, Jin, Y, Cheung, JPY, Feng, X, Sze, KY, Lu, WW   +8 more
core   +1 more source

Effects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats

Scientific Reports, 2017
The aim of this study was to prevent female osteoporosis using strength training (ST), raloxifene (Ral) or a combination of ST plus Ral during the natural female aging process, specifically in the periestropause period.
Camila Tami Stringhetta-Garcia, Samuel Rodrigues Lourenço Morais, Fernanda Fernandes, Melise Jacon Perez-Ueno, Ricardo de Paula Almeida, Mário Jefferson Quirino Louzada, Antonio Hernandes Chaves-Neto, Edilson Ervolino, Rita Cássia Menegati Dornelles   +8 more
doaj   +1 more source

Spectrum of microarchitectural bone disease in inborn errors of metabolism: a cross-sectional, observational study

Orphanet Journal of Rare Diseases, 2020
Background Patients diagnosed with inborn errors of metabolism (IBEM) often present with compromised bone health leading to low bone density, bone pain, fractures, and short stature. Dual-energy X-ray absorptiometry (DXA) is the current gold standard for
Karamjot Sidhu, Bilal Ali, Lauren A. Burt, Steven K. Boyd, Aneal Khan   +4 more
doaj   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Compartment‐specific effects of muscle strength on bone microarchitecture in women at high risk of osteoporosis

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background It is well known that skeletal integrity is influenced by the musculature. Poor muscle strength (i.e. sarcopenia) is considered a major predictor of fragility fractures. While this observation appears particularly relevant for older women with
Alexander Simon, Hannah S. Schäfer, Felix N. Schmidt, Julian Stürznickel, Michael Amling, Tim Rolvien   +5 more
doaj   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

Advanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh, Hosni Cherif, Matthew Mannarino, Juiena Sagir, Magali Millecamps, Jean A. Ouellet, Laura S. Stone, Lisbet Haglund   +7 more
wiley   +1 more source

Bone Mass and Microarchitecture in CKD Patients with Fracture [PDF]

Journal of the American Society of Nephrology, 2010
Patients with predialysis chronic kidney disease (CKD) have increased risk for fracture, but the structural mechanisms underlying this increased skeletal fragility are unknown. We measured areal bone mineral density (aBMD) by dual-energy x-ray absorptiometry at the spine, hip, and radius, and we measured volumetric BMD (vBMD), geometry, and ...
Thomas L, Nickolas, Emily, Stein, Adi, Cohen, Valerie, Thomas, Ronald B, Staron, Donald J, McMahon, Mary B, Leonard, Elizabeth, Shane   +7 more
openaire   +2 more sources

Association between sensitivity to thyroid hormones and trabecular bone score in euthyroid individuals: a population-based cross-sectional study

BMC Musculoskeletal Disorders
Background Thyroid hormone is a known pivotal factor that affects bone metabolism; however, whether bone microarchitecture is associated with thyroid hormone sensitivity is poorly understood.
Zihan Chen, Yuxiong Chen, Yuanmeng Li, Zhiwei Leng, Naishi Li, Weibo Xia   +5 more
doaj   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Assessment of microarchitecture and crystal structure of hydroxyapatite in osteoporosis

Universa Medicina, 2016
Osteoporosis is characterized by lower bone mineral density (BMD) and microarchitectural degeneration, which tends to increase bone fragility and fracture risk.
Zairin Noor, Sutiman B Sumitro, Mohammad Hidayat, Agus Hadian Rahim, Ahmad Taufiq   +4 more
doaj   +1 more source