Results 21 to 30 of about 186,000 (307)

A genetic correlation scan identifies blood proteins associated with bone mineral density

BMC Musculoskeletal Disorders, 2022
Background Osteoporosis is a common metabolic bone disease that is characterized by low bone mass. However, limited efforts have been made to explore the functional relevance of the blood proteome to bone mineral density across different life stages ...
Jiawen Xu, Shaoyun Zhang, Haibo Si, Yi Zeng, Yuangang Wu, Yuan Liu, Mingyang Li, Limin Wu, Bin Shen   +8 more
doaj   +1 more source

Adjusting bone mass for differences in projected bone area and other confounding variables: an allometric perspective. [PDF]

, 2002
The traditional method of assessing bone mineral density (BMD; given by bone mineral content [BMC] divided by projected bone area [Ap], BMD = BMC/Ap) has come under strong criticism by various authors. Their criticism being that the projected bone "area"
Roger L. Holder, Nevill, AM, Holder, Roger, Maffulli, Nicola, Lau, Joseph T. F., Warren T. K. Lee, Lee, WTK, Jack C. Y. Cheng, Nevill, Alan M., Alan M. Nevill, Lee, Warren T. K., Lau, JTF, Joseph T. F. Lau, Maffulli, N, Leung, Sophie S. S. F., Holder, Roger L., Cheng, Jack C. Y., Nicola Maffulli, Cheng, JCY, Leung, SSSF, Sophie S. S. F. Leung   +20 more
core   +1 more source

Anthropometric models of bone mineral content and areal bone mineral density based on the bone mineral density in childhood study [PDF]

Osteoporosis International, 2014
New models describing anthropometrically adjusted normal values of bone mineral density and content in children have been created for the various measurement sites. The inclusion of multiple explanatory variables in the models provides the opportunity to calculate Z-scores that are adjusted with respect to the relevant anthropometric parameters ...
Short, David F., Gilsanz, Vicente, Kalkwarf, Heidi J., Lappe, Joan M., Oberfield, Sharon, Shepherd, John A., Winer, Karen K., Zemel, Babette S., Hangartner, Thomas N.   +8 more
openaire   +4 more sources

Quantitative Ultrasound of Cortical Bone in the Femoral Neck Predicts Femur Strength: Results of a Pilot Study [PDF]

, 2013
Article first published online: 15 JAN 2013 Pour consulter la version éditeur DOI: 10.1002/jbmr.1742A significant risk of femoral neck (FN) fracture exists for men and women with an areal bone mineral density (aBMD) higher than the osteoporotic range ...
GRONDIN, Julien, ENGELKE, Klaus, Reinhard Barkmann, GRIMAL, Quentin, Quentin Grimal, Sandra Guérard, Glüer, Claus-C., Julien Grondin, GUÉRARD, Sandra, Klaus Engelke, GLÜER, Claus-C, BARKMANN, Reinhard, Claus‐C Glüer, Pascal Laugier, LAUGIER, Pascal   +14 more
core   +1 more source

Polymorphisms in genes involved in the NF-κB signalling pathway are associated with bone mineral density, geometry and turnover in men [PDF]

, 2011
<p><b>Introduction:</b> In this study, we aimed to investigate the association between single nucleotide polymorphisms (SNPs) within two genes involved in the NF-kappa B cascade (GPR177 and MAP3K14) and bone mineral density (BMD ...
Wu, Frederick C., O'Neill Terence W., Wu Frederick C., Pendleton Neil, Casanueva, Felipe F., Judith E. Adams, Giwercman, Aleksander, Vanderschueren, Dirk, Holliday, Kate L., Frederick C Wu, Boonen, Steven, Thang S Han, Bartfai, G., Gyorgy Bartfai, Giwercman Aleksander, Ilpo T Huhtaniemi, Terence W. O'Neill, Punab Margus, Adams, J.E., null null, Pendleton, Neil, Pye Stephen R., Kate L. Holliday, Boonen, S., Han, T.S., Michael E. Lean, Holliday, K.L., Stephen R Pye, Huhtaniemi, Ilpo T., Lean, M.E., Dirk Vanderschueren, Adams, Judith E., Margus Punab, Borghs Herman, Felipe F. Casanueva, Judith E Adams, Lean Michael E., Wu, F.C., Herman Borghs, Kula, K., Forti, Gianni, Punab, Margus, Lean, Michael E., Finn, Joseph D., EMAS Study Group, O'Neill, T.W., Finn, J.D., Borghs, Herman, Kula Krzysztof, Joseph D Finn, Thomson, W., Delnaz Roshandel, Huhtaniemi, I.T., Stephen R. Pye, Terence W O'Neill, Giwercman, A., Holliday Kate L., Punab, M., Ward, Kate A., Neil Pendleton, Pye, Stephen R., Casanueva, F.F., Roshandel, Delnaz, Forti Gianni, Kula, Krzysztof, Casanueva Felipe F., Krzysztof Kula, O'Neill, Terence W., Borghs, H., Thang S. Han, Frederick C. Wu, Boonen Steven, Huhtaniemi Ilpo T., Casanueva Freijo, Felipe, Vanderschueren, D., Pendleton, N., Vanderschueren Dirk, Ward, K.A., Forti, G., Han, Thang S., Kate A Ward, Pye, S.R., Ward Kate A., Aleksander Giwercman, Han Thang S., Finn Joseph D., Gianni Forti, Steven Boonen, Bartfai, Gyorgy, Roshandel, D., Adams Judith E., Kate L Holliday, Kate A. Ward, Thomson Wendy, Bartfai Gyorgy, Michael E Lean, Wendy Thomson, Ilpo T. Huhtaniemi, Thomson, Wendy, Joseph D. Finn, Felipe F Casanueva, Roshandel Delnaz   +101 more
core   +1 more source

Causal association of epigenetic aging and osteoporosis: a bidirectional Mendelian randomization study

BMC Medical Genomics, 2023
Background The relationship between aging and osteoporosis is well established. However, the relationship between the body's physiological age, i.e. epigenetic age, and osteoporosis is not known.
Xinyu Liang, Wei Shi, Xinglong Zhang, Ran Pang, Kai Zhang, Qian Xu, Chunlei Xu, Xin Wan, Wenhao Cui, Dong Li, Zhaohui Jiang, Zhengxuan Liu, Hui Li, Huafeng Zhang, Zhijun Li   +14 more
doaj   +1 more source

Prediction of bone mineral density in CT using deep learning with explainability

Frontiers in Physiology, 2023
Bone mineral density (BMD) is a key feature in diagnosing bone diseases. Although computational tomography (CT) is a common imaging modality, it seldom provides bone mineral density information in a clinic owing to technical difficulties.
Jeong-Woon Kang, Chunsu Park, Dong-Eon Lee, Jae-Heung Yoo, MinWoo Kim   +4 more
doaj   +1 more source

The ESR1 (6q25) locus is associated with calcaneal ultrasound parameters and radial volumetric bone mineral density in European men [PDF]

, 2011
<p><b>Purpose:</b> Genome-wide association studies (GWAS) have identified 6q25, which incorporates the oestrogen receptor alpha gene (ESR1), as a quantitative trait locus for areal bone mineral density (BMD(a)) of the hip and lumbar ...
Lean, Michael E. J., Holliday Kate L., Gielen, Evelien, Ward, Kate A., Gielen Evelien, O'Neill Terence W., Pendleton Neil, Judith E. Adams, Neil Pendleton, Giwercman, Aleksander, Pye, Stephen R., Vanderschueren, Dirk, Holliday, Kate L., Boonen, Steven, Forti Gianni, Labrie Fernand, Kula, Krzysztof, Thang S Han, Krzysztof Kula, Lean Michael E. J., O'Neill, Terence W., Gyorgy Bartfai, Thang S. Han, Boonen Steven, Huhtaniemi Ilpo T., Michael E. J. Lean, Casanueva Freijo, Felipe, Giwercman Aleksander, Ilpo T Huhtaniemi, Terence W. O'Neill, Labrie, Fernand, Punab Margus, Giwercman, Aleksander,, Vanderschueren Dirk, null null, Wu, Frederick C.W., Han, Thang S., Wu Frederick C. W., Wu, Frederick C. W., Pendleton, Neil, Lund University., Pye Stephen R., Kate A Ward, Kate L. Holliday, Wu, Frederick C W, Ward Kate A., Lean, Michael E.J., Stephen R Pye, Michael E J Lean, Huhtaniemi, Ilpo T., Lean, Michael E J, Aleksander Giwercman, Han Thang S., Finn Joseph D., Dirk Vanderschueren, Gianni Forti, Adams, Judith E., Lean, M.E.J., Margus Punab, Borghs Herman, Judith E Adams, Felipe Casanueva, Steven Boonen, Herman Borghs, Evelien Gielen, Bartfai, Gyorgy, Forti, Gianni, Punab, Margus, Fernand Labrie, Frederick C. W. Wu, Finn, Joseph D., Adams Judith E., Casanueva, Felipe, Kate L Holliday, Kate A. Ward, Borghs, Herman, Kula Krzysztof, Joseph D Finn, Thomson Wendy, Casanueva Felipe, Bartfai Gyorgy, Wendy Thomson, Ilpo T. Huhtaniemi, Thomson, Wendy, Frederick C W Wu, Joseph D. Finn, Stephen R. Pye, Terence W O'Neill, EMAS study group   +88 more
core   +1 more source

Bone Mineral Density Among Long-term Users of Hormonal Contraception (Contraception and Bone Mineral Density) [PDF]

Al-Azhar International Medical Journal
Background: Hormonal contraceptives that involve steroids have a high success rate and are commonly used. The use of these contraceptives can have positive and negative effects on health, including bone health.
Hanaa Abd El Hameed El Ebeisy, Nahed Ezzat Mahmoud, Hanaa Taha Kandeel, Shaimaa Mahmoud Saad El Tawwab   +3 more
doaj   +1 more source

Bone mineral: update on chemical composition and structure [PDF]

, 2009
Bone mineral: update on chemical composition and ...
Combes, Christèle, Drouet, Christophe, Glimcher, Melvin J., Rey, Christian   +3 more
core   +1 more source