Effect of Oral Alendronate on Bone Mineral Density and the Incidence of Fractures in Postmenopausal Osteoporosis [PDF]
New England Journal of Medicine, 1995 BACKGROUND Postmenopausal osteoporosis is a serious health problem, and additional treatments are needed. METHODS We studied the effects of oral alendronate, an aminobisphosphonate, on bone mineral density and the incidence of fractures and height loss ...
Bell, Norman H., , M.D. +17 more
core +4 more sources
BMC Medical Genomics, 2023 Background The relationship between aging and osteoporosis is well established. However, the relationship between the body's physiological age, i.e. epigenetic age, and osteoporosis is not known.
Xinyu Liang +14 more
doaj +1 more source
Bone Mineral Density and Stroke [PDF]
Stroke, 2003 Background and Purpose— We sought to assess the long-term predictive usefulness of bone mineral density (BMD) for stroke incidence and stroke mortality. Methods— The First National Health and Nutrition Examination Survey data ...
Michael E, Mussolino +2 more
openaire +2 more sources
A non-synonymous coding change in the CYP19A1 gene Arg264Cys (rs700519) does not affect circulating estradiol, bone structure or fracture [PDF]
, 2011 Background The biosynthesis of estrogens from androgens is catalyzed by aromatase P450 enzyme, coded by the CYP19A1 gene on chromosome 15q21.2. Genetic variation within the CYP19A1 gene sequence has been shown to alter the function of the enzyme.
Wang, J.Z. +8 more
core +3 more sources
Microstructural, Densitometric and Metabolic Variations in Bones from Rats with Normal or Altered Skeletal States [PDF]
, 2013 Background: High resolution μCT, and combined μPET/CT have emerged as non-invasive techniques to enhance or even replace dual energy X-ray absorptiometry (DXA) as the current preferred approach for fragility fracture risk assessment.
Anez-Bustillos, Lorenzo +7 more
core +7 more sources
Does a Novice Technician Produce Results Similar to That of an Experienced DXA Technician When Assessing Body Composition and Bone Mineral Density? [PDF]
, 2019 Dual energy X-ray absorptiometry is a commonly used clinical assessment tool for body composition and bone mineral density, which is gaining popularity in athletic cohorts.
Climstein, Mike +3 more
core +1 more source
Factors associated with low bone density in patients referred for assessment of bone health [PDF]
, 2013 Background: To identify factors that predict low bone mineral density (BMD) in pediatric patients referred for dual-energy x-ray absorptiometry assessments.
Giancaterino, Courtney +3 more
core +1 more source
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
, 2006 BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra +14 more
core +4 more sources
Association of total testosterone status with bone mineral density in adults aged 40–60 years
Journal of Orthopaedic Surgery and Research, 2021 Objective Evidence linking total testosterone and bone mineral density (BMD) in adults is very limited. According to our review of the literature, only a few reports have focused on the relationship between total testosterone and bone mineral density in ...
Nan Wang, Lixiang Wang, Chengcheng Huang
doaj +1 more source
Assessing osteoporosis in the young adult [PDF]
, 2015 Osteoporosis in the young adult is a relatively rare phenomenon, and its diagnosis needs careful assessment of the affected person. The emphasis in the assessment of bone health is gradually shifting from a simple quantitative assessment of bone mineral ...
Ahmed, Syed Faisal +2 more
core +1 more source