Results 221 to 230 of about 4,065,576 (293)

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2246-2260, November 2026.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Fecal Microbiota Transplantation: A Promising Therapeutic Strategy Targeting the Microbiota–Gut–Brain Axis in Anorexia Nervosa

Brain and Behavior, Volume 16, Issue 11, November 2026.
Gut dysbiosis in anorexia nervosa may impair microbiota–gut–brain signaling through metabolic, immune, and vagal pathways. Fecal microbiota transplantation is being investigated as a potential strategy to restore host–microbiome balance, support a healthier microbial composition, and improve gastrointestinal function, appetite, and mood.
Shawn L. Kwok, Yu‐Chen Xiao, Xian‐Bin Cai   +2 more
wiley   +1 more source

Resveratrol Modulates Bone Metabolism Through SIRT1‐Mediated NF‐κB Inhibition: Molecular Mechanisms and Therapeutic Implications

Cell Biochemistry and Function, Volume 44, Issue 11, November 2026.
ABSTRACT Osteoporosis and associated skeletal pathologies impose a staggering global health burden, disproportionately impacting elderly populations and postmenopausal women. At the root of excessive bone resorption and stalled osteogenesis lie persistent oxidative stress and chronic inflammation.
Seyyed Hossein Khatami, Faezeh Gouhari, Alireza Manafi‐Rasi, Maryam Fallah, Sajad Ehtiati, Ahmad Reza Ahmadi Abdashti, Mohsen Ariannik, Shahin Talebi, Diba Rafienejad, Mina Fakhrzadegan, Parasta Heidari, Reza Zandi   +11 more
wiley   +1 more source

Body Composition Phenotypes and Their Metabolic Associations in Treatment‐Naïve Patients With Newly Diagnosed Type 2 Diabetes: A DXA‐Based Cluster Analysis

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
Using dual‐energy X‐ray absorptiometry clustering of 185 treatment‐naïve type 2 diabetes patients, we identified four body‐composition phenotypes. Central‐obesity and high‐fat–high‐muscle clusters carried the highest fatty liver disease and hyperuricemia risk, whereas the low‐muscle cluster carried the highest osteoporosis risk.
Xintong Zhang, Rui Zhang, Tao Jiang
wiley   +1 more source

Age‐Related Patterns of Relative Energy Deficiency in Sport (REDs) Symptoms and Key Performance Factors in Adolescent Biathletes

European Journal of Sport Science, Volume 26, Issue 11, November 2026.
ABSTRACT Relative Energy Deficiency in Sport (REDs) impairs health and performance, but age‐related patterns in its emergence remain unclear. This study examines RED symptoms in adolescent biathletes at season‐start and their link to end‐of‐season performance.
Therese Fostervold Mathisen, Inger Johanne Løkkevik, Anne Mette Rustaden, Christine Sundgot‐Borgen, Lindsay Macnaughton, Helge E. Lundberg, Jorunn Sundgot‐Borgen   +6 more
wiley   +1 more source

Diabetic Peripheral Neuropathy With Low Appendicular Muscle Mass Is Associated With Osteoporosis, Falls, and Fractures

Journal of Diabetes, Volume 18, Issue 11, November 2026.
Diabetics have higher risks of osteoporosis, falls, and fractures; higher grip strength predicts lower risks. In both cross‐sectional and longitudinal data, diabetic patients with both peripheral neuropathy and low appendicular muscle mass have the highest risks of osteoporosis and falls.
Biao Zheng, Yongze Zhang, Dan Liang, Ximei Shen, Lingning Huang, Fengying Zhao, Sunjie Yan   +6 more
wiley   +1 more source

Exploring causal associations between the plasma proteome and bone mineral density: a Mendelian randomization study. [PDF]

Endocr Connect
Lv K, Fang J, Wang S, Xing X, Zhu R.
europepmc   +1 more source

Association between triglyceride-glucose index and total trabecular bone score in US adults: A cross-sectional study. [PDF]

Medicine (Baltimore)
Xu H, Xu H, Luo J, Zhao J.
europepmc   +1 more source

Women With Bipolar Disorder are at Increased Risk of Sarcopenia

Bipolar Disorders, Volume 28, Issue 7, November 2026.
ABSTRACT Introduction While bipolar disorder is associated with significant comorbidity, little is known about the musculoskeletal health of individuals with bipolar disorder. Thus, we aimed to investigate the association between bipolar disorder and muscle strength, mass, quality and sarcopenia.
Lana J. Williams, Amanda L. Stuart, Michael Berk, Shae E. Quirk, Emma C. West, Heli Koivumaa‐Honkanen, Risto Honkanen, Jeremi Heikkinen, Jessica A. Davis, D. Kavindi Weerasinghe, Julie A. Pasco   +10 more
wiley   +1 more source

The genetic association between osteoprotegerin (OPG) gene polymorphisms and bone mineral density (BMD) in postmenopausal women: A meta-analysis: Erratum. [PDF]

Medicine (Baltimore), 2019
europepmc   +1 more source