Results 131 to 140 of about 2,491,420 (247)
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying +6 more
wiley +1 more source
Effects of bone morphogenetic proteins on epithelial repair. [PDF]
Hou Y +4 more
europepmc +1 more source
Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration
Wan-Geun La,1 Min Jin,1 Saibom Park,1,2 Hee-Hun Yoon,1 Gun-Jae Jeong,1 Suk Ho Bhang,1 Hoyoung Park,1,2 Kookheon Char,1,2 Byung-Soo Kim1,31School of Chemical and Biological Engineering, Seoul National University, Seoul, Republic of Korea; 2The National ...
La WG +8 more
core
Carrier systems for bone morphogenetic proteins: An overview of biomaterials used for dentoalveolar and maxillofacial bone regeneration. [PDF]
Arias-Betancur A +4 more
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Abstract Background The clinical efficacy of growth factors in regenerative procedures may depend on both dosage and sustained delivery during critical phases of healing. This study aimed to evaluate in vitro release kinetics of platelet‐derived growth factor‐BB (PDGF‐BB) from various graft materials, including recombinant human PDGF‐BB (rhPDGF‐BB ...
Farahnaz Fahimipour +4 more
wiley +1 more source
Formation of neural and epidermal lineages during the differentiation of human embryonal carcinomacells [PDF]
Within the ectoderm of the developing human embryo, cell fate determination is largely modulated by factors activated by cell-to-cell signalling. In vertebrates, ectoderm primarily differentiates into neural cells that make up the central nervous system ...
Christie, Victoria Buyers
core
Abstract Objectives Hereditary polyposis syndromes in children are rare, heterogeneous disorders associated with significant morbidity and long‐term risk of malignancy. Current data on their presentation, management, and outcomes in pediatric populations remain limited.
Shlomi Cohen +9 more
wiley +1 more source
Coordination of iron homeostasis by bone morphogenetic proteins: Current understanding and unanswered questions. [PDF]
Fisher AL, Babitt JL.
europepmc +1 more source

