Results 221 to 230 of about 69,320 (294)

30 Years of Enamel Matrix Derivative (EMD): Biological Foundations and Systematic Review With Meta‐Analyses Across Multiple Clinical Indications

open access: yesJournal of Periodontal Research, EarlyView.
EMD is one of the few biological agents with human histologic evidence supporting periodontal regeneration. This is reflected in improved clinical outcomes when used in regenerative surgery for intrabony defects. Despite its biological plausibility for broader therapeutic applications, further high‐quality randomized clinical trials are needed to ...
Richard J. Miron   +10 more
wiley   +1 more source

Bone Grafts: Everything You Need to Know

open access: yesJournal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen   +5 more
wiley   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

open access: yesJournal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed   +1 more
wiley   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye   +6 more
wiley   +1 more source

Clinical and Radiologic Outcomes of NOVOSIS (rhBMP‐2 With Hydroxyapatite Carrier) Grafting for Scaphoid Waist Nonunion: A Preliminary Clinical Study

open access: yesOrthopaedic Surgery, EarlyView.
NOVOSIS (rhBMP‐2 with hydroxyapatite carrier) grafting filled the scaphoid waist defect and promoted bone union after double headless screw fixation, offering a feasible alternative to autologous bone grafting. ABSTRACT Objective Scaphoid nonunion remains a challenging problem due to limited vascularity and carpal malalignment. Although autologous bone
Jisu Park   +3 more
wiley   +1 more source

Bone morphogenetic proteins and inner ear development. [PDF]

open access: yesJ Zhejiang Univ Sci B, 2019
Ma JY   +5 more
europepmc   +1 more source

Inflammation and mechanical force‐induced bone remodeling

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon   +6 more
wiley   +1 more source

Advantages of horizontal centrifugation of platelet‐rich fibrin in regenerative medicine and dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated.
Nima Farshidfar   +6 more
wiley   +1 more source

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